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Identification and characterization of novel associations in the casp8/als2cr12 region on chromosome 2 with breast cancer risk
(Oxford University Press (OUP), 2014-08-28)
Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility, we carried out dense genotyping of this ...
Towards linked open gene mutations data
(Springer Nature, 2012-01-01)
Background: With the advent of high-throughput technologies, a great wealth of variation data is being produced. Such information may constitute the basis for correlation analyses between genotypes and phenotypes and, in ...
Minimum information about tolerogenic antigen-presenting cells (mitap): a first step towards reproducibility and standardisation of cellular therapies
(PeerJ, 2016-08-30)
Cellular therapies, with tolerogenic antigen-presenting cells (tolAPC) show great promise for the treatment of autoimmune diseases and for the prevention of destructive immune responses after transplantation The methodologies ...
Health of farmed fish: its relation to fish welfare and its utility as welfare indicator
(Springer Nature, 2011-06-18)
This brief review focuses on health and biological function as cornerstones of fish welfare. From the function-based point of view, good welfare is reflected in the ability of the animal to cope with infectious and ...
Effects of levothyroxine therapy on pregnancy outcomes in women with subclinical hypothyroidism
(Mary Ann Liebert Inc, 2016-07-01)
Background: Subclinical hypothyroidism (SCH) has been associated with increased risk of adverse pregnancy outcomes in some, but not all, studies. Uncertainty remains regarding the impact of levothyroxine (LT4) therapy on ...
Establishment of the european meningococcal strain collection genome library (emsc-gl) for the 2011 to 2012 epidemiological year
(European Centre for Disease Control and Prevention (ECDC), 2018-05-17)
Invasive meningococcal disease surveillance in Europe combines isolate characterisation and epidemiological data to support public health intervention. A representative European Meningococcal Strain Collection (EMSC) of ...
Endoplasmic reticulum stress: at the crossroads of inflammation and metabolism in hepatocellular carcinoma development
(Elsevier BV, 2014-09-01)
Steatohepatitis is a cause of hepatocellular carcinoma development; however, the underlying mechanisms are poorly defined. In this issue of Cancer Cell, Nakagawa and colleagues demonstrate that activation of endoplasmic ...
Detection and management of diabetes in england: results from the health survey for england
(Springer Nature, 2017-09-25)
Introduction: As part of a control strategy current guidance in the UK recommends more intense surveillance of HbA1C levels among those of South-east Asian or Chinese ethnicity above specified BMI thresholds. The objective ...
Soft robotic sleeve supports heart function
(American Association for the Advancement of Science (AAAS), 2017-01-18)
There is much interest in form-fitting, low-modulus, implantable devices or soft robots that can mimic or assist in complex biological functions such as the contraction of heart muscle. We present a soft robotic sleeve ...
Stabilization of metastatic lesions affecting the second cervical vertebra
(Medknow, 2015-01-01)
Purpose: Metastatic spine disease is an ever-increasing burden on health care systems. Certain levels in the spine confer unique biomechanical characteristics and hence are of interest. Isolated C2 lesions are rare. We ...