Now showing items 1-6 of 6

    • Characterization of an amplified piezoelectric actuator for multiple reference optical coherence tomography 

      O'Gorman, Sean; Neuhaus, Kai; Alexandrov, Sergey; Hogan, Josh; Wilson, Carol; McNamara, Paul M.; Leahy, Martin (Optica, 2018-08-30)
      The characterization of an amplified piezoelectric actuator (APA) as a new axial scanning method for multiple-reference optical coherence tomography (MR-OCT) is described. MR-OCT is a compact optical imaging device based ...
    • Label-free ultra-sensitive visualization of structure below the diffraction resolution limit 

      Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, Martin (Wiley, 2018-03-23)
      For both fundamental study of biological processes and early diagnosis of diseases, information about nanoscale changes in tissue and cell structure is crucial. Nowadays, almost all currently known nanoscopy methods rely ...
    • Performance review of multiple reference versus time domain optical coherence tomography 

      Neuhaus, Kai; McNamara, Paul M.; Alexandrov, Sergey; O'Gorman, Seán; Hogan, Josh; Wilson, Carol; Leahy, Martin J. (IEEE, 2018-04-19)
      We present a detailed characterization of noise sources in multiple reference optical coherence tomography (MR-OCT) compared to time-domain OCT (TD-OCT). The noise characteristics were modeled based on the TD-OCT noise ...
    • Simultaneous en-face imaging of multiple layers with multiple reference optical coherence tomography 

      Neuhaus, Kai; O’Gorman, Seán; McNamara, Paul M.; Alexandrov, Sergey; Hogan, Josh; Wilson, Carol; Leahy, Martin J. (Society of Photo-optical Instrumentation Engineers, 2017-08-22)
      A technique based on multiple reference optical coherence tomography (MR-OCT) is proposed for simultaneous imaging at multiple depths. The technique has been validated by imaging a reference sample and a fingerprint in-vivo. ...
    • Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization 

      Alexandrov, Sergey; McNamara, Paul M.; Das, Nandan; Zhou, Yi; Lynch, Gillian; Hogan, Josh; Leahy, Martin (AIP Publishing, 2019-09-16)
      Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers ...
    • Ultra-sensitive label free imaging below the resolution limit 

      Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, James J. (SPIE (Society of Photo-optical Instrumentation Engineers) Digital Library, 2019-02-02)
      Almost all known nanoscopy methods rely upon the contrast created by fluorescent labels attached to the object of interest. This causes limitations on their applicability to in vivo imaging. A new label-free spectral ...