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Immunogenicity of allogeneic mesenchymal stem cells
(2012)
Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule-1 (VCAM-1). We investigated whether ...
Gene therapy in transplantation: Toward clinical trials
(Thompson, 2009)
The genetic modification of organs or cells is an attractive approach to protect allogeneic transplants from acute rejection and other complications. The transplant setting offers a unique opportunity to utilise ex vivo ...
Future directions in managing aniridia-associated keratopathy
(Elsevier, 2023-05-04)
Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia
and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal
transparency and thereby loss of ...