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Functional coupling of beta(3)-adrenoceptors and large conductance calcium-activated potassium channels in human uterine myocytes
(Endocrine Society, 2005-07-02)
Context: beta(3)-Adrenoreceptor modulation in human myometrium during pregnancy is linked functionally to myometrial inhibition. Maxi-K+ channels (BKCa) play a significant role in modulating cell membrane potential and ...
Transcription factor binding site identification using the Self-Organizing Map
(Oxford Open Journals, 2005-05-01)
Motivation: The automatic identification of over-represented motifs present in a collection of sequences continues to be a challenging problem in computational biology. In this paper, we propose a self-organizing map of ...
Characterisation of the differentially regulated trout protein 1 (DRTP1) gene in rainbow trout (Oncorhynchus mykiss)
(Elsevier, 2008-10-04)
Increased levels of differentially regulated trout protein 1 (DRTP1) mRNA transcripts have been reported in fish after activation of the acute phase response. While the function of the DRTP1 protein still remains to be ...
Acute phase gene expression in rainbow trout (Oncorhynchus mykiss) after exposure to a confinement stressor: A comparison of pooled and individual data
(Elsevier, 2009-06-09)
This study set out to investigate whether differential expression of genes for acute phase proteins in rainbow trout (Oncorhynchus mykiss) could be induced by confinement stress, a non-invasive method of activating the ...
Citizenship and structured dependency: the implications of policy design for senior political power
(Cambridge University Press, 2009)
This paper argues that the structured dependency thesis must be extended to incorporate political power. It outlines a political framework of analysis with which to identify who gains and who loses from social policy. I ...
Youth Mentoring as a Tool for Community and Civic Engagement: Reflections on Findings of an Irish Research Study
(Taylor and Francis, 2009-12-07)
Youth mentoring programs such as Big Brothers Big Sisters (BBBS) are traditionally considered to be a vehicle for youth development rather than community development. In fact, the notion that the one-to-one engagement that ...
Youth Mentoring in Ireland: Weighing up the Benefits and Challenges
(Irish Youth Work Press, 2007)
Internationally, mentoring for young people has become increasingly attractive to policy makers as a micro-level response to the needs of young people deemed to be
¿at risk¿ or in need of support. The Big Brothers Big ...
Evaluation of a novel real-time PCR test based on the ssrA gene for the identification of group B streptococci in vaginal swabs.
(2009)
Despite the implementation of prevention guidelines, early-onset group B streptococci (GBS) disease remains a cause of neonatal morbidity and mortality worldwide. Strategies to identify women who are at risk of transmitting ...
Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells
(Mary Ann Liebert, 2009-10)
The aim of this study was to assess the feasibility of transplanting mesenchymal stem cells (MSCs), genetically modified to express glial-derived neurotrophic factor (GDNF), to the contused rat spinal cord, and to subsequently ...
Health promoting school indicators: schematic models for children.
(Emerald, 2007-06)
Purpose - The purpose of this paper is to outline a three-stage process for engaging with students to develop school level indicators of health; in sequential class groups students first generated, then categorised indicators ...