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Enhancing the immunomodulatory capacity and therapeutic potential of mesenchymal stromal cell-derived small extracellular vesicles through cytokine licensing
(NUI Galway, 2023-09-12)
The immunomodulatory capacity of mesenchymal stromal cells (MSCs) is well
established, and is being explored as a cellular therapy for the treatment of various
inflammatory-based conditions. In recent years, the role of ...
Influence of tissue source on the therapeutic potential of mesenchymal stromal cells
(NUI Galway, 2023-05-11)
Advanced therapy medicinal products (ATMPs) offer revolutionary new prospects for the
treatment of conditions of unmet medical need. Among them, Mesenchymal Stromal Cells
(MSCs) have emerged as promising candidates for ...
Novel high-resolution imaging modalities for monitoring in vitro models of cartilage degeneration and mesenchymal stem cell therapy in osteoarthritis
(NUI Galway, 2023-06-20)
Osteoarthritis (OA) is a chronic disease of synovial joints characterized by progressive
degeneration of articular cartilage causing pain and disability in millions of people worldwide.
Current imaging systems used for ...