Browsing University of Galway Theses (PhD Theses) by Subject "Macrocycles"
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Carbohydrates in the synthesis of macrocycles and glycoclusters
(NUI Galway, 2019-01-28)This thesis deals with efforts to generate new bioactive organic compounds. The main focus has been on the use of carbohydrate building blocks for synthesis of both macrocyclic compounds and glycoclusters for biological ... -
Design and synthesis of macrocycles, peptides and coiled coils with sugar connections
(2016-06-09)Migrastatin is a secondary metabolite that is formed from the bacterium Streptomyces platensis. This compound has shown promising anti-metastatic activity by inhibiting tumour cell migration. Published derivatives of this ...