Browsing University of Galway Theses (PhD Theses) by Subject "CRISPR/Cas9"
Now showing items 1-2 of 2
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Human stem cell modelling for heart disease of long QT syndrome
(NUI Galway, 2022-04-29)Sudden cardiac death (SCD) in otherwise healthy young people is a public health priority. Long QT syndrome (LQTS) is the commonest life-threatening cardiac arrhythmia contributing to SCD under 40 years old with an estimated ... -
Investigating nucleolar dynamics in karyotypically normal human cells by fluorescent protein tagging of genes encoding key nucleolar proteins
(NUI Galway, 2022-06-14)The nucleolus, the site of ribosome biogenesis, is the largest membrane-less structure or organelle in the eukaryotic nucleus. It forms around arrays of ribosomal gene (rDNA) repeats termed nucleolar organizer regions ...