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Now showing items 11-14 of 14
Hydrogen bonding networks and solid-state conversions in benzamidinium salts
(2015-07-14)
Ten benzamidinium salts of carboxylic acids, amides, and sulfonamides have been crystallized from solution. Single-crystal X-ray analyses revealed various hydrogen bonding motifs which ate discussed in terms of supramolecular ...
Use of sublimation catalysis and polycrystalline powder templates for polymorph control of gas phase crystallization
(American Chemical Society, 2018-05-08)
In pursuit of a solvent-free green alternative to solution-based processes, we have applied the combined use of catalytic additives and polycrystalline powder templates for polymorph control of gas phase crystallization ...
Cocrystal forms of the BCS class IV drug sulfamethoxazole
(American Chemical Society, 2018-05-23)
Sulfamethoxazole, smz, is an antibiotic that is classified as a Biopharmaceutics Classification System (BCS) class IV, low solubility and low permeability drug. Cocrystal formation has been examined in an attempt to improve ...
Application of ball milling for highly selective mechanochemical polymorph transformations
(American Chemical Society, 2018-06-07)
Milling is an important secondary processing technique in the manufacture of pharmaceuticals, primarily used as a particle size reduction process. p-Aminobenzoic acid (PABA), m-aminobenzoic acid (MABA), o-aminobenzoic acid ...