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Conversion of gel-forming crystal needles to easily processable more equant crystals Using high-shear ultralow attrition agitation: accelerated Ostwald ripening without crystal attrition
(American Chemical Society, 2019-02-01)
We demonstrate the first examples of the transformation of gel-forming crystal needles into easily processable more equant crystals by accelerated Ostwald ripening without detectable crystal attrition. Using high solution ...
Investigation of the formation of drug-drug cocrystals and coamorphous systems of the antidiabetic drug gliclazide
(Elsevier, 2019-02-23)
The antidiabetic drug gliclazide (GLZ) has a slow absorption rate and a low bioavailability due to its poor solubility. GLZ is often prescribed along with an antihypertensive, as many diabetic patients have coexistent ...
Supramolecular stacking in a high Z′ calix[8]arene–porphyrin assembly
(Royal Society of Chemistry, 2019-11-15)
A co-crystal structure of sulfonato-calix[8]arene (sclx8) and trimethylanilinium-porphyrin (tmap) at 1.0 Å resolution is reported. The oppositely charged macrocycles formed an alternating stacked assembly. Crystal packing ...