Now showing items 1-2 of 2

    • Revealing biomedically relevant cell and lectin type-dependent structure–activity profiles for glycoclusters by using tissue sections as an assay platform 

      Kaltner, Herbert; Manning, Joachim C.; García Caballero, Gabriel; Di Salvo, Claudia; Gabba, Adele; Romero-Hernández, Laura L.; Knospe, Clemens; Wu, Dan; Daly, Harrison C.; O'Shea, Donal F.; Gabius, Hans-Joachim; Murphy, Paul V. (Royal Society of Chemistry, 2018-08-14)
      The increasing realization of the involvement of lectin-glycan recognition in (patho)physiological processes inspires envisioning therapeutic intervention by high-avidity/specificity blocking reagents. Synthetic glycoclusters ...
    • Stereoselective epimerizations of glycosyl thiols 

      Doyle, Lisa M.; O'Sullivan, Shane; Di Salvo, Claudia; McKinney, Michelle; McArdle, Patrick; Murphy, Paul V. (American Chemical Society, 2017-10-17)
      Glycosyl thiols are widely used in stereoselective S-glycoside synthesis. Their epimerization from 1,2-trans to 1,2-cis thiols (e.g., equatorial to axial epimerization in thioglucopyranose) was attained using TiCl4, while ...