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Applications of raman spectroscopy in biopharmaceutical manufacturing: A short review
(Sage Publications, 2017-05-23)
The production of active pharmaceutical ingredients (APIs) is currently undergoing its biggest transformation in a century.
The changes are based on the rapid and dramatic introduction of protein- and macromolecule-based ...
Low-content quantification in powders using Raman spectroscopy: a facile chemometric approach to sub 0.1% limits of detection.
(American Chemical Society, 2015-02-23)
A robust and accurate analytical methodology for low-content (<0.1%) quantification in the
solid-state using Raman spectroscopy, sub-sampling, and chemometrics was demonstrated using
a piracetam–proline model. The method ...
Rapid characterization and quality control of complex cell culture media solutions using Raman spectroscopy and chemometrics
(2010)
The use of Raman spectroscopy coupled with chemometrics for the rapid identification, characterization, and quality assessment of Complex cell culture media components used for industrial mammalian cell culture was ...
Monitoring cell culture media degradation using surface enhanced Raman scattering (SERS) spectroscopy
(Elsevier (Science Direct), 2014-06-13)
The quality of the cell culture media used in biopharmaceutical manufacturing is a crucial factor affecting bioprocess performance and the quality of the final product. Due to their complex composition these media are ...