Browsing by Title

Now showing items 4589-4608 of 14646

    • Estrogen induces repression of the breast cancer and salivary gland expression gene in an estrogen receptor   dependent manner 

      Bretschneider, N.; Brand, H.; Miller, N.; Lowery, A. J.; Kerin, M. J.; Gannon, F.; Denger, S. (American Association for Cancer Research (AACR), 2008-01-01)
      The focus of this study is on the expression and regulation of the estrogen-regulated breast cancer and salivary gland expression (BASE) gene that may function as a breast cancer marker. In MCF7 cells, BASE is repressed ...

    • Estrogen plus estrogen receptor antagonists alter mineral production by osteoblasts in vitro 

      Brennan, O.; O’Brien, F.; McNamara, L. (Thieme Publishing Group, 2011-11-28)
      In early postmenopausal women, estrogen withdrawal is associated with increased bone turnover leading to bone loss and increased risk of fracture. Recent studies have suggested that the remaining bone tissue is significantly ...

    • Estrogen withdrawal in osteocytes results in altered integrin function, primary cilium elongation, and increased pro-osteoclastogenic signalling 

      Geoghegan, Ivor (NUI Galway, 2020-06-28)
      Osteocytes are the main mechanosensitive cells within bone. They detect changes in the mechanical environment and transduce them into biochemical responses (RANKL, OPG, and sclerostin) that regulate bone remodelling by ...

    • Estrogen withdrawal, increased breast cancer risk and the kras-variant 

      McVeigh, Terri P; Jung, Song-Yi; Kerin, Michael J; Salzman, David W; Nallur, Sunitha; Nemec, Antonio A; Dookwah, Michelle; Sadofsky, Jackie; Paranjape, Trupti; Kelly, Olivia; Chan, Elcie; Miller, Nicola; Sweeney, Karl J; Zelterman, Daniel; Sweasy, Joann; Pilarski, Robert; Telesca, Donatello; Slack, Frank J; Weidhaas, Joanne B (Informa UK Limited, 2015-05-11)
      The KRAS-variant is a biologically functional, microRNA binding site variant, which predicts increased cancer risk especially for women. Because external exposures, such as chemotherapy, differentially impact the effect ...

    • Ethical challenges in qualitative research: Examples from practice 

      Houghton, Catherine E.; Casey, Dympna; Shaw, David; Murphy, Kathy (RCN Publishing Ltd., 2010-10-22)
      This article examines the many ethical challenges that are specific to qualitative research. These challenges concern the issues of informed consent procedures, the researcher-participant relationship, risk-benefit ratio, ...

    • An ethical commitment: responsibility, cosmopolitanism and care in the internationalised university 

      Coate, Kelly (Routledge, 2013-10)
      The internationalization of higher education has decisively moved from being a scholarly tradition of mobility across borders to an almost purely economic concern. This is a trend that is most pronounced in countries such ...

    • Ethical dilemmas in the development-security nexus: A human development and capabilities approach 

      Khoo, Su-Ming (Centre for Global Education, 2019)
      The development-security nexus marks a paradigm shift for development, security and humanitarian practice, with implications for education and development education. This article explores zigzag changes, initially towards ...

    • Ethical Issues in Internet Research: International Good Practice and Irish Research Ethics Documents 

      Felzmann, Heike (Research-publishing.net, 2013)
      This chapter discusses the main research ethical concerns that arise in internet research and reviews existing research ethical guidance in the Irish context in relation to its application to internet research. The ...

    • Ethical review and childrens research in Ireland 

      Felzmann, Heike; Sixsmith, Jane; O'Higgins, Siobhan; Nic Gabhainn, Saoirse; Ui Chonnachtaigh, Sorcha (OMCYA, 2010-03)
      A substantial increase in research into the lives of children has been experienced in Ireland over the last few years. This increase is not only in the amount of research undertaken but also in the multi-disciplinary range ...

    • Ethics and assisted dying in the Republic of Ireland 

      McKeown O'Donovan, Annie (NUI Galway, 2021-09-13)
      ‘Ethics and Assisted Dying in the Republic of Ireland’ argues that active assistance in dying can be morally permissible in limited contexts. Where an individual is suffering from an irremediable chronic or terminal illness ...

    • The ethics of narrative form in Gaskell, Dickens, and Eliot 

      Pacious, Kathleen (2016-05-03)
      This thesis explores Elizabeth Gaskell’s North and South, Charles Dickens’s Our Mutual Friend, and George Eliot’s Daniel Deronda through the lens of rhetorical narratology to offer conclusions for realism, metafiction, and ...

    • Ethnomethodology: Time for a revisit? A discussion paper 

      Dowling, Maura (Elsevier, 2007-07-05)
      The aim of this paper is to provide a comprehensive overview of ethnomethodology and explore its usefulness as a methodology for nursing. Ethnomethodology was conceived through the writings of Harold Garfinkel, an American ...

    • Etiology of non–cystic fibrosis bronchiectasis in adults and its correlation to disease severity 

      Lonni, Sara; Chalmers, James D.; Goeminne, Pieter C.; McDonnell, Melissa J.; Dimakou, Katerina; De Soyza, Anthony; Polverino, Eva; Van de Kerkhove, Charlotte; Rutherford, Robert; Davison, John; Rosales, Edmundo; Pesci, Alberto; Restrepo, Marcos I.; Torres, Antoni; Aliberti, Stefano (American Thoracic Society, 2015-12-01)
      Rationale: Testing for underlying etiology is a key part of bronchiectasis management, but it is unclear whether the same extent of testing is required across the spectrum of disease severity. Objectives: The aim of the ...

    • Ets-1 is a transcriptional mediator of oncogenic nitric oxide signaling in estrogen receptor-negative breast cancer 

      Switzer, Christopher H; Cheng, Robert Y-S; Ridnour, Lisa A; Glynn, Sharon A; Ambs, Stefan; Wink, David A (Springer Nature, 2012-09-12)
      Introduction: The Ets-1 transcription factor is a candidate breast cancer oncogene that regulates the expression of genes involved in tumor progression and metastasis. Ets-1 signaling has also been linked to the development ...

    • EU Bewildered by Ireland's Attitude to Peacekeeping Force for Macedonia 

      Murphy, Ray (The Irish Times, 2003)

    • The EU-protected slug geomalacus maculosus: an investigation into its phylogenetics, population densities in conifer plantations and its gut microbial community 

      Reich, Inga (2016-04-04)
      Geomalacus maculosus is an EU protected Lusitanian slug species which is only found in Ireland and Northern Iberia. It inhabits largely undisturbed habitats such as blanket bogs and forests where it feeds on lower plants ...

    • Eucaari ion spectrometer measurements at 12 european sites – analysis of new particle formation events 

      Manninen, H. E.; Nieminen, T.; Asmi, E.; Gagné, S.; Häkkinen, S.; Lehtipalo, K.; Aalto, P.; Vana, M.; Mirme, A.; Mirme, S.; Hõrrak, U.; Plass-Dülmer, C.; Stange, G.; Kiss, G.; Hoffer, A.; Törő, N.; Moerman, M.; Henzing, B.; de Leeuw, G.; Brinkenberg, M.; Kouvarakis, G. N.; Bougiatioti, A.; Mihalopoulos, N.; O'Dowd, C.; Ceburnis, D.; Arneth, A.; Svenningsson, B.; Swietlicki, E.; Tarozzi, L.; Decesari, S.; Facchini, M. C.; Birmili, W.; Sonntag, A.; Wiedensohler, A.; Boulon, J.; Sellegri, K.; Laj, P.; Gysel, M.; Bukowiecki, N.; Weingartner, E.; Wehrle, G.; Laaksonen, A.; Hamed, A.; Joutsensaari, J.; Petäjä, T.; Kerminen, V.-M.; Kulmala, M. (Copernicus GmbH, 2010-08-25)
      We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range similar to 1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions ...

    • Eurasian haplotype m phragmites australis (cav.) trin. ex steud., 1841 invasion in minnesota, usa: a baseline for further monitoring in the upper mississippi watershed 

      Melchior, Paul; Weaver, Robbyn (Regional Euro-Asian Biological Invasions Centre Oy (REABIC), 2016-01-01)
      The cryptic invasion of North American aquatic ecosystems by non-native haplotypes of Phragmites australis (Cav.) Trin. ex Steud., 1841, has been well documented. Most research has focused on eastern Canada, and the eastern ...

    • Eureca one – 27 nations, one europe, one registry: a prospective observational analysis over one month in 27 resuscitation registries in europe – the eureca one study protocol 

      Wnent, Jan; Masterson, Siobhán; Gräsner, Jan-Thorsten; Böttiger, Bernd W; Herlitz, Johan; Koster, Ruud W; Rosell Ortiz, Fernando; Tjelmeland, Ingvild; Maurer, Holger; Bossaert, Leo (Springer Nature, 2015-01-01)
      Background: There is substantial variation in the incidence, likelihood of attempted resuscitation and outcomes from out-of-hospital cardiac arrest (OHCA) across Europe. A European, multi-centre study provides the opportunity ...

    • Eureca one⿿27 nations, one europe, one registry 

      Gräsner, Jan-Thorsten; Lefering, Rolf; Koster, Rudolph W.; Masterson, Siobhán; Böttiger, Bernd W.; Herlitz, Johan; Wnent, Jan; Tjelmeland, Ingvild B.M.; Ortiz, Fernando Rosell; Maurer, Holger; Baubin, Michael; Mols, Pierre; HadžibegoviĿ, Irzal; Ioannides, Marios; Škulec, Roman; Wissenberg, Mads; Salo, Ari; Hubert, Hervé; Nikolaou, Nikolaos I.; Lóczi, Gerda; Svavarsdóttir, Hildigunnur; Semeraro, Federico; Wright, Peter J.; Clarens, Carlo; Pijls, Ruud; Cebula, Grzegorz; Correia, Vitor Gouveia; Cimpoesu, Diana; Raffay, Violetta; Trenkler, Stefan; Markota, Andrej; Strömsöe, Anneli; Burkart, Roman; Perkins, Gavin D.; Bossaert, Leo L.; Kaufmann, Marc; Thaler, Markus; Maier, Martin; Prause, Gerhard; Trimmel, Helmut; de Longueville, Diane; Preseau, Thierry; Biarent, Dominique; Melot, Christian; Mpotos, Nicolas; Monsieurs, Koen; Van de Voorde, Patrick; Vanhove, Marie; Lievens, Pascale; Faniel, Mathias; Keleuva, Slobodanka; Lazarevic, Milan; Ujevic, Radmila Majhen; Devcic, Mato; Bardak, Branka; Barisic, Fabijan; Anticevic, Silvija Hunyadi; Georgiou, Marios; Truhláſ, Anatolij; Knor, Jiſí; Smržová, Eva; Sviták, Roman; Šín, Robin; Mokrejš, Petr; Lippert, Freddy K.; Hallikainen, Juhana; Hoikka, Marko; Iirola, Timo; Jama, Timo; Jäntti, Helena; Jokisalo, Raimo; Jousi, Milla; Kirves, Hetti; Kuisma, Markku; Laine, Jukka; Länkimäki, Sami; Loikas, Petri; Lund, Vesa; Määttä, Teuvo; Nal, Heini; Niemelä, Heimo; Portaankorva, Petra; Pylkkänen, Marko; Sainio, Marko; Setälä, Piritta; Tervo, Jerry; Väyrynen, Taneli; Jama, Timo; Murgue, Davy; Champenois, Anne; Fournier, Marc; Meyran, Daniel; Tabary, Romain; Avondo, Aurélie; Gelin, Gelin; Simonnet, Bruno; Joly, Marc; Megy-Michoux, Isabelle; Paringaux, Xavier; Duffait, Yves; Vial, Michael; Segard, Julien; Narcisse, Sophie; Hamban, David; Hennache, Jonathan; Thiriez, Sylvain; Doukhan, Mathieu; Vanderstraeten, Carine; Morel, Jean-Charles; Majour, Gilles; Michenet, Corinne; Tritsch, Laurent; Dubesset, Marc; Peguet, Olivier; Pinero, David; Guillaumee, Fréderic; Fuster, Patrick; Ciacala, Jean-François; Jardel, Benoît; Letarnec, Jean-Yves; Goes, Frank; Gosset, Pierre; Vergne, Muriel; Bar, Christian; Branche, Fabienne; Prineau, Stevens; Lagadec, Steven; Cornaglia, Carole; Ursat, Cécile; Bertrand, Philippe; Agostinucci, Jean-Marc; Nadiras, Pierre; de Linares, Géraldine Gonzales; Jacob, Line; Revaux, François; Pernot, Thomas; Roudiak, Nathalie; Ricard-Hibon, Agnès; Villain-Coquet, Laurent; Beckers, Stefan; Hanff, Thomas; Strickmann, Bernd; Wiegand, Nicolai; Wilke, Petra; Sues, Harald; Bogatzki, Stefan; Baumeier, Wolfgang; Pohl, Kai; Werner, Bert; Fischer, Hans; Zeng, Torsten; Popp, Erik; Günther, Andreas; Hochberg, Andreas; Lechleuthner, Alex; Schewe, Jens-Christian; Lemke, Hans; Wranze-Bielefeld, Erich; Bohn, Andreas; Roessler, Markus; Naujoks, Frank; Sensen, Frank; Esser, Torben; Fischer, Matthias; Messelken, Martin; Rose, Christopher; Schlüter, Gabriele; Lotz, Wolfgang; Corzilius, Michael; Muth, Claus-Martin; Diepenseifen, Christian; Tauchmann, Björn; Birkholz, Torsten; Flemming, Andreas; Herrmann, Stefanie; Kreimeier, Uwe; Kill, Clemens; Marx, Frank; Schröder, Ralph; Lenz, Wolfgang; Botini, Glykeria; Grigorios, Barakos; Giannakoudakis, Nikolaos; Zervopoulos, Michail; Papangelis, Dimitrios; Petropoulou-Papanastasiou, Sofia; Liaskos, Themistoklis; Papanikolaou, Spyridon; Karabinis, Andreas; Zentay, Attila; ÿorsteinsson, Hólmgeir; Gilsdóttir, Anna; Birgisson, Svavar A.; Guðmundsson, Fjölnir Freyr; Hreiðarsson, Hallgrímur; ÿrnason, Björgvin; Hermannsson, Hermann; Björnsson, Gísli; Friðriksson, Brynjar ÿór; Baldursson, Gunnar; Höskuldsson, ÿrmann; Valgarðsdottir, Jórunn; ÿsmundardóttir, Matthildur; Guðmundsson, Guðmundur; Kristjánsson, Hjörtur; ÿórarinsson, Eyþór Rúnar; Guðlaugsson, Jón; Skarphéðinsson, Sigurður; Peratoner, Alberto; Santarelli, Andrea; Sabetta, Cesare; Gordini, Giovanni; Sesana, Giovanni; Giudici, Riccardo; Savastano, Simone; Pellis, Tommaso; Beissel, Jean; Uhrig, Jean; Manderscheid, Tom; Klop, Marco; Stammet, Pascal; Koch, Marc; Welter, Philippe; Schuman, Robert; Bruins, Wendy; Amin, Hesam; Braa, Nina; Bratland, Staale; Buanes, Eirik Alnes; Draegni, Tomas; Johnsen, Knut Roar; Mathisen, Wenche Torunn; Oedegaarden, Terje; Oppedal, Marie; Reksten, Alf Stolt-Nielsen; Roedsand, Mats Eirik; Steen-Hansen, Jon Erik; Dyrda, Marta; Frejlich, Anna; MaciĿg, Sſawomir; Osadnik, Sonia; Weryk, Ireneusz; Mendonça, Eugénio; Freitas, Carlos; Cruz, Pinto; Caldeira, Carmo; Barros, José; Vale, Luis; Brazão, António; Jardim, Nuno; Rocha, Fernanda; Duarte, Ricardo; Fernandes, Nicodemos; Ramos, Pedro; Jardim, Margarida; Reis, Miguel; Ribeiro, Romulo; Zenha, Sérgio; Fernandes, Jorge; Francisco, Juan; Assis, David; Abreu, Fernanda; Freitas, Dinarte; Ribeiro, Leonardo; Azevedo, Paulo; Calafatinho, Débora; Jardim, Rui; Pestana, Aleixo; Faria, Rui; Oprita, Bogdan; Grasu, Alis; Nedelea, Paul; Sovar, Sorina; Agapi, Florin; KliĿkoviĿ, Aleksandar; LaziĿ, Aleksandra; NikoliĿ, Bogdan; Zivanovic, Bogdan; MartinoviĿ, Branislav; MilenkoviĿ, Dušan; Damir, HuseinoviĿ; Koprivica, Jovanka; JakšiĿ, Kornelija Horvat; Pajor, Margit; MiliĿ, Saša; VidoviĿ, Mirko; Glamoclija, Radojka Petrovic; Andjelic, Sladjana; Sladjana, Vlajovic; BabiĿ, Zlatko; Fišer, Zlatko; Androvic, Peter; Bajerovska, Lubica; Chabron, Miroslav; Dobias, Viliam; Havlikova, Eva; Horanova, Bozena; Kratochvilova, Renata; Kubova, Dana; Murgas, Jan; Patras, Juraj; Simak, Ladislav; Snarskij, Vladimir; Zaviaticova, Zuzana; Zuffova, Marcela; Roig, Francesc Escalada; Santos, Luis Sánchez; Sucunza, Alfredo Echarri; Cordero Torres, Juan A.; Muñoz, Guadalupe Inza; del Valle, Marta Martínez; Rozalen, Isabel Ceniceros; Sánchez, Enrique Martín; Berlanga, María Victoria Raúl Canabal; Olalde, Karlos Ibarguren; Ruiz Azpiazu, José I.; García-Ochoa, María José; López-Navarro, Rafael Zoyo; Adsuar Quesada, José M.; Cortés Ramas, José A.; Mellado Vergel, Francisco J.; López Messa, Juan B.; del Valle, Patricia Fernández; Anselmi, Luciano; Benvenuti, Breganzona Claudio; Batey, Nigel; Ambulance, Yorkshire; Booth, Scott; Bucher, Patricia; Deakin, Charles D.; Duckett, Jay; Ji, Chen; Loughlin, Nancy; Lumley-Holmes, Jenny; Lynde, Jessica; Mersom, Frank; Ramsey, Carly; Robinson, Clare; Spaight, Robert; Dosanjh, Sukhdeep; Virdi, Gurkamal; Whittington, Andrew (Elsevier BV, 2016-08-01)