Browsing Data Science Institute by Author "Mehdi, Muntazir"

Now showing items 1-13 of 13

    • Advancing clinical research by semantically interconnecting aggregated medical data information in a secure context 

      Antoniades, Athos; Aristodimou, Aristos; Georgousopoulo, Christos; Forgó, Nikolaus; Gledson, Ann; Hasapis, Panagiotis; Vandeleur, Caroline; Perakis, Konstantinos; Sahay, Ratnesh; Mehdi, Muntazir; Demetriou, Christiana A.; Strippoli, Marie-Pierre F.; Giotaki, Vasiliki; Ioannidi, Myrto; Tian, David; Tozzi, Federica; Keane, John; Pattichis, Constantinos (Springer Verlag, 2017-03-22)
      Electronic Health Records (EHRs) contain an increasing wealth of medical information. When combined with molecular level data, they enhance the understanding of the underlying biological mechanisms of diseases, enabling ...

    • Demonstrating a linked data platform for finite element biosimulations of cochlear mechanics 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Hasapis, Panagiotis; Sahay, Ratnesh (CEUR-WS.org, 2015-10-11)
      Biosimulations employ Finite Element Method (FEM) to simulate complex biological systems in order to understand different aspects of human organs. The applications of FEM biosimulations range from human ear cochlear mechanics, ...

    • Demonstrating a linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Raza, Saleem; Hasapis, Panagiotis; Sahay, Ratnesh (IEEE, 2016-02-04)
      Healthcare experts have recently turned towards the use of Biosimulation models to understand the multiple or different causative factors that cause impairment in human organs. The applications of biosimulations have been ...

    • Detecting inner-ear anatomical and clinical datasets in the linked open data (LOD) cloud 

      Mehdi, Muntazir; Iqbal, Aftab; Khan, Yasar; Decker, Stefan; Sahay, Ratnesh (CEUR-WS.org, 2015-10-15)
      Linked Open Data (LOD) Cloud is a mesh of open datasets coming from different domains. Among these datasets, a notable amount of datasets belong to the life sciences domain linked together forming an interlinked “Life ...

    • Extending inner-ear anatomical concepts in the Foundational Model of Anatomy (FMA) ontology 

      Khan, Yasar; Mehdi, Muntazir; Jha, Alokkumar; Raza, Saleem; Freitas, Andre; Jones, Marggie; Sahay, Ratnesh (IEEE, 2015-11-02)
      The inner ear is physically inaccessible in living humans, which leads to unique difficulties in studying its normal function and pathology as in other human organs. Recently, biosimulation model has gained a significant ...

    • Linked Biomedical Dataspace: Lessons Learned integrating Data for Drug Discovery 

      Hasnain, Ali; Kamdar, Maulik; Deus, Helena; Mehdi, Muntazir; Decker, Stefan (Springer, 2014)
      The increase in the volume and heterogeneity of biomedical data sources has motivated researchers to embrace Linked Data (LD) technologies to solve the ensuing integration challenges and enhance information discovery. As ...

    • A linked data platform for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Decker, Stefan; Sahay, Ratnesh (ACM, 2015-09-16)
      Biosimulation models have been recently introduced to understand the exact causative factors that give rise to impairment in human organs. Finite Element Method (FEM) provides a mathematical framework to simulate dynamic ...

    • A linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Freitas, Andre; Jares, Joao; Raza, Saleem; Hasapis, Panagiotis; Sahay, Ratnesh (IEEE, 2016-02-04)
      Biosimulation models are used to understand the multiple or different causative factors that cause impairment in human organs. Finite Element Method (FEM) provide a mathematical framework to simulate dynamic biological ...

    • A linked data visualiser for finite element biosimulations 

      Mehdi, Muntazir; Khan, Yasar; Jares, Joao; Freitas, Andre; Jha, Alok Kumar; Sakellarios, Antonis; Sahay, Ratnesh (World Scientific Publishing, 2016)
      Biosimulation models are used to understand the multiple or different causative factors that cause impairment in human organs. Finite Element Method (FEM) provide a mathematical framework to simulate dynamic biological ...

    • Linked functional annotation for differentially expressed gene (DEG) demonstrated using Illumina Body Map 2.0 

      Jha, Alokkumar; Khan, Yasar; Iqbal, Aftab; Zappa, Achille; Mehdi, Muntazir; Sahay, Ratnesh; Rebholz-Schuhmann, Dietrich (CEUR-WS.org, 2015-12-09)
      Semantic Web technologies are core for the integration of disparate data resources. It can be used to exploit data from next generation sequencing (NGS) for therapeutic decisions regarding cancer. In this manuscript, ...

    • A Roadmap for navigating the Life Sciences Linked Open Data Cloud 

      Hasnain, Ali; Sana e Zainab, Syeda; Kamdar, Maulik; Mehmood, Qaiser; Deus, Helena; Mehdi, Muntazir; Decker, Stefan (2014)
      Multiple datasets that add high value to biomedical research have been exposed on the web as a part of the Life Sciences Linked Open Data (LSLOD) Cloud. The ability to easily navigate through these datasets is crucial for ...

    • SAFE: SPARQL federation over RDF data cubes with access control 

      Khan, Yasar; Saleem, Muhammad; Mehdi, Muntazir; Hogan, Aidan; Mehmood, Qaiser; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (BioMed Central, 2017-02-01)
      Several query federation engines have been proposed for accessing public Linked Open Data sources. However, in many domains, resources are sensitive and access to these resources is tightly controlled by stakeholders; ...

    • Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data 

      Jha, Alokkumar; Khan, Yasar; Mehdi, Muntazir; Karim, Md Rezaul; Mehmood, Qaiser; Zappa, Achille; Rebholz-Schuhmann, Dietrich; Sahay, Ratnesh (BioMed Central, 2017-09-19)
      Next Generation Sequencing (NGS) is playing a key role in therapeutic decision making for the cancer prognosis and treatment. The NGS technologies are producing a massive amount of sequencing datasets. Often, these datasets ...