Browsing Research Institutes and Centres by Author "Laffey, John G."

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    • Effects and mechanisms of action of sildenafil citrate in human chorionic arteries 

      Maharaj, Chrisen H.; O'Toole, Daniel; Lynch, Tadhg; Carney, John; Jarman, James; Higgins, Brendan D.; Morrison, John J.; Laffey, John G. (2009)
      Objectives Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine ...

    • Improved diagnosis of SARS-CoV-2 by using nucleoprotein and spike protein fragment 2 in quantitative dual ELISA tests 

      De Marco Verissimo, Carolina; O'Brien, Carol; López Corrales, Jesús; Dorey, Amber; Cwiklinski, Krystyna; Lalor, Richard; Doyle, Jack M.; Field, Stephen; Masterson, Claire; Ribes Martinez, Eduardo; Hughes, Gerry; Bergin, Colm; Walshe, Kieran; McNicholas, Bairbre; Laffey, John G.; Dalton, John P.; Kerr, Colm; Doyle, Sean (Cambridge University Press, 2021-06-08)
      The novel coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), is the causative agent of the 2020 worldwide coronavirus pandemic. Antibody testing is useful for diagnosing historic infections of a ...