Browsing Research Institutes and Centres by Author "Doyle, Karen M."

Now showing items 1-3 of 3

    • Characterization of the ‘White’ appearing clots that cause acute ischemic stroke 

      Mereuta, Oana Madalina; Rossi, Rosanna; Douglas, Andrew; Molina Gil, Sara; Fitzgerald, Seán; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Ceder, Eric; Dunker, Dennis; Nordanstig, Annika; Redfors, Petra; Jood, Katarina; Magoufis, Georgios; Psychogios, Klearchos; Tsivgoulis, Georgios; O'Hare, Alan; Power, Sarah; Brennan, Paul; Nagy, András; Vadász, Ágnes; Brinjikji, Waleed; Kallmes, David F.; Szikora, Istvan; Rentzos, Alexandros; Tatlisumak, Turgut; Thornton, John; Doyle, Karen M. (Elsevier, 2021-09-28)
      Objectives Most clots retrieved from patients with acute ischemic stroke are ‘red’ in color. ‘White’ clots represent a less common entity and their histological composition is less known. Our aim was to investigate the ...

    • High-resolution scanning electron microscopy for the analysis of three-dimensional ultrastructure of clots in acute ischemic stroke 

      Mereuta, Oana Madalina; Fitzgerald, Seán; Christensen, Trace A.; Jaspersen, Adam L.; Dai, Daying; Abbasi, Mehdi; Puttappa, Tejaswini; Kadirvel, Ram; Kallmes, David F.; Doyle, Karen M.; Brinjikji, Waleed (BMJ Publishing Group, 2020-12-23)
      Background: Characterization of acute ischemic stroke (AIS) clots has typically focused on two dimensional histological analysis of the thrombus. The three dimensional (3D) architecture and distribution of components ...

    • Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy 

      Mereuta, Oana Madalina; Doyle, Karen M. (BMJ Publishing Group, 2021-05-11)
      Background Several animal studies have demonstrated that mechanical thrombectomy (MT) for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the histological changes in human cerebral arteries following ...