Browsing University of Galway Theses by Author "Frank, Uri"
Now showing items 1-8 of 8
-
Cell fate commitment during nervous system establishment: from stem cells to neurons
Chrysostomou, Eleni (NUI Galway, 2020-07-06)Members of the early-branching metazoan phylum of Cnidaria are well-recognized as a sister group to bilaterians making them an ideal candidate to study the evolution of the eumetazoan nervous system. I began to unravel the ... -
Characterisation of histone variants in the cnidarian Hydractinia
Török, Anna (NUI Galway, 2019-02-21)Hydractinia is a marine hydrozoan cnidarian that has been a model organism for developmental biology for over a century. Very few studies have been carried out on chromatin biology in cnidarians. To date, there is no ... -
Characterization of PIWI+ stem cells in Hydractinia
McMahon, Emma (2018-02-23)Hydractinia is a colonial marine invertebrate and a member of the phylum Cnidaria. It represents a very powerful tool for studying basic developmental biology and differentiation due to the presence of a population of stem ... -
Development of transgenic and genome editing tools to study the role of Notch signalling in Hydractinia echinata
Gahan, James (2016)Hydractinia is a colony forming marine invertebrate and a member of the phylum Cnidaria. Members of this genus have been models for developmental biologists for over a century and feature many characters of evolutionary ... -
DNA methylation and zygotic genome activation during early embryogenesis of animals
Febrimarsa, Febrimarsa (NUI Galway, 2020-10-25)Upon fertilization, after the fusion of two pronuclei, the newly formed zygotic genome is transcriptionally inactive. Hence, early animal development is driven by maternal RNAs and proteins. The zygotic genome becomes ... -
Transcriptome analysis in Hydractinia echinata reveals species-specific and phylum-wide gene loss
Doonan, Liam B. (NUI Galway, 2018-05-04)The advances and subsequent widespread use of next-generation sequencing, in particular transcriptomics, has allowed biologists to approach questions and study many more powerful and previously underappreciated model animals ... -
An unexpected role for Nanos in cnidarian neural stem cell fate determination
Kanska, Justyna (2012-09)The mechanisms of lineage commitment and acquiring specific cell fate remain obscure and require investigating the role of particular genes involved in these complex processes. To address this issue, I studied the role of ... -
Wnt signalling in the hydrozoan Hydractinia echinata
Hensel, Katrin (2013-09-11)Canonical Wnt signalling controls many developmental processes in metazoans including primary axis formation in embryonic development and stem cell decision making. The evolutionary history of Wnt signalling and its ancestral ...