Browsing University of Galway Theses by Subject "Diabetes"
Now showing items 1-14 of 14
-
Autologous peripheral blood endothelial progenitor cells as a potential therapy for diabetic critical limb ischemia
(NUI Galway, 2023-10-20)[No abstract] -
Building the evidence base for the development and implementation of an Irish national digital Type 2 Diabetes prevention programme
(NUI Galway, 2022-12-09)Background: Type 2 Diabetes Mellitus (T2DM) represents a major public health concern. Over one million annual deaths worldwide are attributed to the disease, making it the ninth leading cause of mortality. In Ireland, the ... -
A core outcome set for the treatment of pregnant women with pregestational diabetes: An international consensus study
(NUI Galway, 2021-09-10)Background Meaningful comparisons between studies evaluating interventions of pregnant women with pre-gestational diabetes mellitus (PGDM) are limited due to the heterogeneity in outcome selection and reporting. The aim ... -
Development of a mesenchymal stromal cell / collagen scaffold product for treatment of diabetic wounds
(NUI Galway, 2022-08-23)Foot ulceration is a major complication of diabetes mellitus, which results in significant human suffering and a major burden on healthcare systems. Mesenchymal stromal cells (MSCs) emerged as a promising therapeutic ... -
Development of novel biomaterials and medical devices to improve diabetes treatment and ambient cell transportation
(NUI Galway, 2023-02-08)Diabetes mellitus is a global pandemic affecting to more than 500 million people worldwide, with Type 1 diabetics being the most at risk due to life-threatening hyper and hypoglycaemic complications. Islet transplantation ... -
An experimental investigation on the biomechanics of bone fragility in type 2diabetes
(NUI Galway, 2023-10-11)Type 2 diabetic patients experience up to a 3-fold increase in bone fracture risk. Paradoxically, type 2 diabetes is associated with a normal or increased bone mineral density (BMD) when compared to non-diabetic patients. ... -
Exploring the effectiveness and implementation of goal-setting techniques in diabetes self-management interventions and structured education programme
(NUI Galway, 2018-09-28)Background. The treatment of diabetes consists of ongoing medical care and continuous self-management. Sub-optimal levels of diabetic control are commonly detected in people with diabetes. Therefore, Healthcare Professionals ... -
Fibrin Mediated Proangiogenic and Secretory Control Gene Therapy for Compromised Wound Healing
(2012-07-18)Chronic or compromised healing is a major clinical problem. Particularly, in diabetes where the disease process hinders the capacity to repair the tissue damage, the patients are more susceptible to chronic ulcers, especially ... -
The importance of a continuum of care before, during and after pregnancy in women with type 1 and type 2 diabetes along the Irish Atlantic seaboard
(2017-04-06)Pregestational diabetes is the most common chronic medical condition to complicate pregnancy and is associated with an increased risk of morbidity and mortality for the mother-offspring pair. Optimising outcomes for this ... -
An investigation into weight mediated conditions as risk factors for the development of autism spectrum disorder in offspring and the application of applied behavior analysis to pre-pregnancy weight behavior
(NUI Galway, 2018-09-03)Obesity (OB) has been identified as one of the greatest health concerns of the present time, due to the universally increasing rates (WHO, 2016). It has been found that a large proportion of the rise of OB is among women ... -
Novel Cell-Based Therapies for the Treatment of Diabetic Ulceration
(2012-02-28)The focus of this research is on developing novel cell based therapies for the treatment of non-healing diabetic foot ulceration. The thesis begins with a concise review of the diabetic foot ulcers. The burden associated ... -
The prevalence of abnormal glucose tolerance up to 5 years after an index pregnancy complicated by gestational diabetes defined using International Association of Diabetes and Pregnancy Study Groups criteria
(2015-09-25)Introduction Gestational diabetes (GDM) is associated with an increased future risk of type 2 diabetes, but the risk among women diagnosed with the International Association of Diabetes and Pregnancy Study Groups (IADPSG) ... -
The role of novel biomarkers in addressing the burden of chronic kidney disease in diabetes mellitus
(NUI Galway, 2022-10-06)Kidney disease due to diabetes (Diabetic Kidney Disease (DKD)) is the leading cause of chronic kidney disease worldwide. It is an underappreciated, often under-recognised component of the overall burden of diabetes. People ... -
Towards an additive manufactured macroencapsulation device for islet cell replacement therapy
(NUI Galway, 2020-07-28)Islet encapsulation devices can induce a Foreign Body Response (FBR) and the formation of a hardened avascular fibrotic capsule. This FBR is heightened when the device features a smooth surface as fibrous tissue is unable ...