Now showing items 1-4 of 4

  • Centriolar and ciliary responses to DNA damage 

    Conroy, Pauline Ciara (2012-09-26)
    Centrosome duplication is tightly controlled and takes place only once every cell cycle. In recent years more light has been shed on the mechanism of centrosome duplication, with key players being identified and characterised. ...
  • Centrosome cohesion: functions of C-NAP1 

    Flanagan, Anne-Marie (2016-01-07)
    Double stranded DNA encodes the genetic material of the cell. Replication and segregation cycles are regulated in order to maintain the integrity of the DNA sequence from one cell cycle to the next. Detection of lesions ...
  • Reverse Genetic Analysis of Pericentrin Functions 

    Wang, Yifan Jr (2012-06-11)
    The centrosome is a subcellular organelle that organises the mitotic spindle microtubules to ensure accurate segregation of chromosomes during cell division. Most animal centrosomes comprise a pair of centrioles which are ...
  • The roles of centrins/caltractins at the centrosome and in genome maintenance 

    Dantas, Tiago Jorge O.G. de Almeida (2012-06-21)
    The principal microtubule-organising centre in animal cells, the centrosome, contains centrin, a small, highly-conserved calcium-binding protein that can be found throughout eukaryotes. Several centrin isoforms exist and ...