Browsing University of Galway Theses by Subject "Biomechanics"
Now showing items 1-10 of 10
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A computational and experimental investigation of tracheobronchial stent performance
(2017-05-25)Tracheobronchial stents are used to relieve blockages in the respiratory tree, typically caused by lung cancer. However, multiple complications can be associated with stents for this indication. In order to be able to ... -
Experimental and computational analysis of the mechanical behavior of poly(lactic-co-glycolic acid) during degradation for medical implant applications
(2016-01-25)Biodegradable polymers such as PLGA have been used in a wide range of biomedical applications due to their hydrolytic degradation and biocompatibility. The mechanical performance of biodegradable polymers during degradation ... -
Experimental and computational investigation of adhesion junction mechanosensation
(2017-02-28)Bone is an adaptive tissue that remodels in response to the mechanical loads placed upon it during normal daily activity. This remodelling process is vital to maintaining the mechanical integrity, mass and structure of ... -
Experimental and computational investigation of atherosclerotic plaque biomechanics
(NUI Galway, 2019-11-22)The overall objective of this thesis is to provide new insights into the composition and biomechanical behaviour of atherosclerotic plaque. Experimental and computational analysis techniques are developed to investigate ... -
An experimental investigation on the biomechanics of bone fragility in type 2diabetes
(NUI Galway, 2023-10-11)Type 2 diabetic patients experience up to a 3-fold increase in bone fracture risk. Paradoxically, type 2 diabetes is associated with a normal or increased bone mineral density (BMD) when compared to non-diabetic patients. ... -
In silico bone tissue engineering - a multiscale and multiphysics approach
(2016-07-26)Mechanical stimulation in terms of fluid flow and mechanical strain can enhance the osteogenesis. Biomaterial scaffolds used in bone tissue engineering experiments have extremely complex geometry, which will result in the ... -
An investigation of the role of body-worn inertial sensing in the analysis of elite swimming performance
(2017-09-29)Swimming is a technically demanding sport that requires ongoing quantitative assessment in order to monitor technical progression and improvements in performance. Traditional methods of monitoring a swimmer’s technique ... -
The mechanical environment of the stem cell niche in bone marrow
(2014-06-13)Understanding how bone marrow mesenchymal stem cells (MSCs) contribute to new bone formation and remodelling in vivo is of principal importance for informing the development of effective bone tissue engineering strategies ... -
Non-linear anisotropic mechanical behaviour of hard and soft tissues
(2015-09-30)The overall objective of this thesis is to develop accurate and rigorous constitutive formulations for the non-linear anisotropic behaviour of soft tissue (arterial) and hard tissues (trabecular bone) at large strains. The ... -
The Role of the Actin Cytoskeleton in the Response of Chondrocytes to Mechanical Loading: A Computational and Experimental Investigation
(2012-09-28)The biomechanisms which govern the response of chondrocytes to mechanical stimuli are poorly understood. This thesis aims to provide a more in depth understanding of chondrocyte biomechanics by focusing on the role of actin ...