Browsing University of Galway Theses by Subject "Mismatch repair"
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Proteins that modulate trinucleotide repeat expansions in human cells
(2012-09-18)Expansions of trinucleotide repeats (TNRs) are the genetic cause of several inherited neurological diseases, such as Huntington's disease, myotonic dystrophy and fragile X syndrome. TNR diseases and their causal expansion ...