Browsing University of Galway Theses by Subject "Extracellular Vesicles"
Now showing items 1-4 of 4
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Current and potential diagnostic modalities in the detection and management of breast cancer
(NUI Galway, 2021-07-06)Global statistics have demonstrated that breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among female patients, accounting for 23 percent of total cancer cases and 14 percent of ... -
Enhancing the immunomodulatory capacity and therapeutic potential of mesenchymal stromal cell-derived small extracellular vesicles through cytokine licensing
(NUI Galway, 2023-09-12)The immunomodulatory capacity of mesenchymal stromal cells (MSCs) is well established, and is being explored as a cellular therapy for the treatment of various inflammatory-based conditions. In recent years, the role of ... -
Extracellular vesicle encapsulated microRNAs and breast cancer
(NUI Galway, 2023-02-24)Breast cancer is the most prevalent cancer among women worldwide. There is a clear need for earlier detection methods and more personalised treatments. Extracellular vesicle encapsulated microRNA (EV-miR) provide novel ... -
Mesenchymal stem cell mediated delivery of Extracellular Vesicle (EV)-encapsulated microRNAs for the treatment of breast cancer
(NUI Galway, 2020-08-04)Mesenchymal Stem Cells (MSCs) hold the ability to home to the site of the tumour and bypass the host immune system. Extracellular Vesicles (EVs) are thought to be a fingerprint of the parent cell and therefore MSC-EVs ...