Browsing University of Galway Theses by Author "Ryan, Aideen E."
Now showing items 1-3 of 3
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Allogeneic cell therapy for osteoarthritis
Lohan, Paul (2016-05-11)Osteoarthritis is a debilitating multi-factorial joint disease which currently has no cure. Due to the significant immune cell mediated component in this disease a therapy which can modulate this inflammation and promote ... -
Investigation of the role of mesenchymal stromal cells in modulating macrophage phenotype and function in the colorectal tumour microenvironment
Leonard, Niamh A. (NUI Galway, 2022-06-28)Colorectal cancer (CRC) is the third most commonly occurring cancer. While there have been improvements in treatment options for patients, it remains the second leading cause of cancer-related deaths worldwide. CRC develops ... -
The role of sialylation in stromal cell-mediated immunosuppression in the colorectal tumour microenvironment
Egan, Hannah (NUI Galway, 2023-04-19)Immunosuppressive tumour microenvironments (TME) inhibit the effectiveness of many immunotherapies. The hypersialylation of cancer cells contributes significantly to this suppressive environment, aiding in tumour immune ...