Browsing University of Galway Theses by Author "McMahon, Siobhan"
Now showing items 1-3 of 3
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Axonal Regeneration Supported by Oligo[poly(ethylene glycol)fumarate] Cell-Loaded Hydrogel Scaffolds in the Transected Rat Spinal Cord
Madigan, Nicolas Niall (2012-04-16)Spinal cord injury results in complete tissue destruction and irreversible loss of neurologic function below the level of the lesion in 40% of patients in Ireland. Tissue engineering using polymer scaffolds offers potential ... -
Ex Vivo slice culture model of rat spinal cord injury as a platform for testing proposed treatment strategies
Ab Patar, Mohd Nor Azim (NUI Galway, 2018-04-13)There are several detrimental events that occur in the aftermath of a spinal cord injury (SCI); these include glial scar formation, accumulation of axon growth inhibitors and immune mediators. These events present challenges ... -
Glycosylation in the injured and regenerating spinal cord, and the influence of biomaterial treatment
Ronan, Rachel (NUI Galway, 2020-02-04)Traumatic spinal cord injury (SCI) results in disruption of tissue integrity leading to a loss of function. There has been minimal success in treating these injuries clinically, due to the inhibitory environment which ...