Browsing University of Galway Theses by Author "Macaluso, Francesca"
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Dissecting the evolution of resistance to microtubule hyper-stabilization
Macaluso, Francesca (NUI Galway, 2024-01-31)When microtubules are hyper-stabilized, they do not provide the proper tension at the kinetochore of the metaphase chromosomes. Low tension leads to the activation of the spindle assembly checkpoint which stops cells ...