Browsing University of Galway Theses by Title
Now showing items 1350-1369 of 2276
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Measuring and improving patient safety in general practice in Ireland
(NUI Galway, 2019-11-15)Due to the large volume of primary care consultations and increasing patient complexity, there is substantial potential for unintentional patient harm. Measuring and monitoring of safety is essential to identify the ... -
Measuring moments: Annotating and quantifying narrative time disruptions in modernist and hypertext fiction
(NUI Galway, 2021-07-30)This project outlines a new method of annotating and quantitatively discussing narrative techniques related to time in fiction. Its principal research questions are, firstly, to determine whether a valid and useful system ... -
The mechanical environment of the stem cell niche in bone marrow
(2014-06-13)Understanding how bone marrow mesenchymal stem cells (MSCs) contribute to new bone formation and remodelling in vivo is of principal importance for informing the development of effective bone tissue engineering strategies ... -
Mechanical evaluation of ovine brain tissue using rheometry and shear wave ultrasound elastography
(NUI Galway, 2023-08-24)The aim of this thesis is to measure the mechanical properties of brain matter to aid clinical decisions in tissue resection. Brain tissue has proven difficult to model in part due to its extreme softness, requiring ... -
The Mechanical Performance of Permanent and Bioabsorbable Metal Stents
(2012-09-13)Developments in metallic coronary stents are toward permanent devices with thinner struts and bioabsorbable devices. To facilitate the development of these promising technologies an improved understanding of thin-strut ... -
Mechanisms of bone marrow-mediated drug resistance in acute myeloid leukaemia
(NUI Galway, 2020-06-12)Acute myeloid leukaemia (AML) is a heterogenous clonal disorder characterised by the accumulation of immature, non-functional and highly proliferative blasts in the bone marrow and periphery. AML has a high relapse rate, ... -
Mechanisms of iron sulfide-based autotrophic denitrification for removal of nutrients and emerging contaminants from carbon-deficient wastewater
(NUI Galway, 2023-09-19)Autotrophic denitrification is a biological nitrogen removal process in which nitrate (NO3 - ) is reduced to nitrogen gas (N2) by chemoautotrophic denitrifying bacteria in the presence of inorganic electron donors ... -
Mechanistic and kinetic study on the anomerisation reaction and application in pharmaceutical research
(NUI Galway, 2024-01-08)It is becoming increasingly apparent that carbohydrate-based pharmaceutically active compounds (PACs) play a key role in pharmaceutical advancement. Many new carbohydrate-based PACs have recently been developed with a ... -
Mechanistic insights into novel cellular therapy strategies for the treatment of corneal allograft rejection
(NUI Galway, 2019-02-14)It has previously been demonstrated by our lab that tolerogenic dendritic cells (tDCs) prolong corneal allograft survival. This study revealed that tDCs had significantly higher levels of sialic acid on the cell surface ... -
Mechanobiological changes during estrogen deficiency leading to bone loss
(NUI Galway, 2019-12-18)Osteoporosis, which predominantly occurs in females, affects 200 million women worldwide and is characterised by bone loss and microarchitectural degradation, which leads to fractures, pain and immobility. Conventional ... -
Mechanobiological origins of osteolysis during bone metastasis
(NUI Galway, 2023-03-28)Metastasis is the final, lethal stage of cancer where cells migrate from a primary tumour site to colonise a secondary organ and is the primary cause of mortality in cancer patients. Breast cancer is the leading cause ... -
Mechanobiological Origins of Osteoporosis
(2013-09-30)The osteocyte is believed to act as the primary sensor of mechanical stimulus in bone, controlling signalling for bone growth and resorption in response to changes in the mechanical demands placed on bones throughout life. ... -
Media accountability in the twenty-first century
(2012-10-02)This thesis provides a comprehensive examination, analysis and assessment of the strengths and weaknesses of the various methods currently used to ensure media accountability in Ireland and in other jurisdictions. It ... -
Media and disability - issues of portrayal and access
(2016-04-29)This thesis begins with the premise that freedom of expression is the cornerstone of a democracy and any limitation on it must be prescribed by law, be in support of a legitimate aim and be necessary in a democratic society. ... -
Media matters: Impact of expansion media on the phenotype of mesenchymal stromal cells
(NUI Galway, 2023-03-02)Despite a long history of investigation and sustained efforts in clinical testing with large numbers of clinical trials being initiated, the number of market authorisations for mesenchymal stromal cell (MSC) therapies ... -
Mediated glucose biosensors for application in continuous glucose monitoring
(NUI Galway, 2023-04-19)Diabetes affects 1 in 11 people globally and requires monitoring of blood glucose levels as a part of its treatment. Initial blood glucose monitoring devices involved finger prick testing at regular intervals daily, a ... -
Mediating alternative imaginaries of aid and development: The possibilities and challenges for contemporary NGOs
(NUI Galway, 2020-03-14)This thesis extends considerations around the role that geography can play in disrupting dominant representational tropes through which Global North publics understand distant people and places. Through a focus on NGO ... -
Medical devices for the minimally invasive delivery of therapeutic cargo for the prevention of heart failure
(NUI Galway, 2020-11-10)Therapeutic advances are increasing the number of patients that survive cardiac disease such as a myocardial infarction, however, current treatments do not fully stop the development of heart failure. Advanced therapeutic ... -
Medical student selection: a mixed methods study
(2015-09-29)Selection to medicine is widely considered the single most important assessment of a doctor's medical career. It is a key deciding factor in the composition of the medical workforce. Selectors have a social responsibility ... -
Medicalisation in Ireland - A mixed methods analysis using the case of statins for primary prevention of cardiovascular disease
(NUI Galway, 2019-05-29)Statins are a class of drugs that lower blood cholesterol levels and were originally used to prevent further recurrences in those with a history of cardiovascular disease (CVD). Over time, their use has been extended to ...