Browsing College of Science by Subject "schizophrenia"
Now showing items 1-2 of 2
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Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders
(Springer Nature, 2013-10-15)Schizophrenia (SZ) and autism spectrum disorders (ASDs) are complex neurodevelopmental disorders that may share an underlying pathology suggested by shared genetic risk variants. We sequenced the exonic regions of 215 genes ... -
Genes regulated by BCL11B during T‐cell development are enriched for de novo mutations found in schizophrenia patients
(Wiley, 2020-07-29)While abnormal neurodevelopment contributes to schizophrenia (SCZ) risk, there is also evidence to support a role for immune dysfunction in SCZ.BCL11B, associated with SCZ in genome-wide association study (GWAS), is a ...