Browsing by Subject "growth-factor-beta"
Now showing items 1-6 of 6
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Co-transfection of decorin and interleukin-10 modulates pro-fibrotic extracellular matrix gene expression in human tenocyte culture
(Springer Nature, 2016-02-10)Extracellular matrix synthesis and remodelling are driven by increased activity of transforming growth factor beta 1 (TGF-beta 1). In tendon tissue repair, increased activity of TGF-beta 1 leads to progressive fibrosis. ... -
Fibrillin-1 in incisional hernias: an immunohistochemical study in scar and non-scar regions of human skin and muscle fasciae
(Wiley-Blackwell, 2008-05-01)Incisional hernias represent one of the most common complications after laparotomy. Specific pre-operative risk factors have not yet been identified. Recent studies indicate that changes in extracellular matrix components ... -
Global gene expression in endometrium of high and low fertility heifers during the mid-luteal phase of the estrous cycle
(Springer Nature, 2014-01-01)Background: In both beef and dairy cattle, the majority of early embryo loss occurs within the first 14 days following insemination. During this time-period, embryos are completely dependent on their maternal uterine ... -
Interleukin-1 accounts for intrarenal th17 cell activation during ureteral obstruction
(Elsevier BV, 2012-02-01)Interleukin 17A-secreting T-helper 17 (Th17) cells are pathogenic in inflammatory kidney diseases, but their intrarenal regulation is poorly understood. In order to better define Th17 cell dynamics during interstitial ... -
Perspective on post-menopausal osteoporosis: establishing an interdisciplinary understanding of the sequence of events from the molecular level to whole bone fractures
(The Royal Society, 2009-10-21)Current drug treatments for post-menopausal osteoporosis cannot eliminate bone fractures, possibly because the mechanisms responsible for bone loss are not fully understood. Although research within various disciplines has ... -
Stimulation of bk virus dna replication by nfi family transcription factors
(American Society for Microbiology, 2011-12-28)BK polyomavirus (BKV) establishes persistent, low-level, and asymptomatic infections in most humans and causes polyomavirus-associated nephropathy (PVAN) and other pathologies in some individuals. The activation of BKV ...