Browsing by Subject "genetic overlap"
Now showing items 1-2 of 2
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A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains
(Wiley-Blackwell, 2017-08-29)This large multi-center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi-modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ... -
Heritability of neuropsychological measures in schizophrenia and nonpsychiatric populations: a systematic review and meta-analysis
(Oxford University Press (OUP), 2016-11-21)Schizophrenia is characterized by neuropsychological deficits across many cognitive domains. Cognitive phenotypes with high heritability and genetic overlap with schizophrenia liability can help elucidate the mechanisms ...