Browsing by Title
Now showing items 3759-3778 of 14646
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DNA hybridisation detection on chemically modified electrodes with bioelectrocatalytic amplification of signal
(2011-12-22)Electrochemical detection of DNA hybridization is a viable alternative to optical and radio-labelled techniques. The benefits of using biosensors based on electrochemical systems are: high sensitivity, possible development ... -
DNA Immobilization and Detection on Cellulose Paper using a Surface Grown Cationic Polymer via ATRP
(American Chemical Society, 2012-02-02)Cationic polymers with various structures have been widely investigated in the areas of medical diagnostics and molecular, biology because of their unique binding properties and capability to interact with biological ... -
DNA mediated chromatin pull-down for the study of chromatin replication
(2011)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. Here we describe a simple experimental ... -
Dna mediated chromatin pull-down for the study of chromatin replication
(Springer Nature, 2011-09-19)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. Here we describe a simple experimental ... -
DNA mediated chromatin pull-down: a novel method for the study of chromatin replication
(2012-04-27)Chromatin replication involves duplicating DNA while maintaining epigenetic information. These processes are critical for genome stability and for preserving cell-type identity. To investigate how these processes are ... -
DNA methylation and zygotic genome activation during early embryogenesis of animals
(NUI Galway, 2020-10-25)Upon fertilization, after the fusion of two pronuclei, the newly formed zygotic genome is transcriptionally inactive. Hence, early animal development is driven by maternal RNAs and proteins. The zygotic genome becomes ... -
Dna polymerase ε associates with the elongating form of rna polymerase ii and nascent transcripts
(Wiley-Blackwell, 2006-11-15)DNA polymerase epsilon co-operates with polymerases alpha and delta in the replicative DNA synthesis of eukaryotic cells. We describe here a specific physical interaction between DNA polymerase epsilon and RNA polymerase ... -
Dna polymerase η modulates replication fork progression and dna damage responses in platinum-treated human cells
(Springer Nature, 2013-11-20)Human cells lacking DNA polymerase eta (pol eta) are sensitive to platinum-based cancer chemotherapeutic agents. Using DNA combing to directly investigate the role of pol eta in bypass of platinum-induced DNA lesions in ... -
Dna repair: location, location, location
(Impact Journals, LLC, 2015-07-10) -
Dna repair: the importance of phosphorylating histone h2ax
(Elsevier BV, 2005-02-01)How phosphorylated histone H2AX, known as gamma-H2AX, functions in the cellular response to DNA double-strand breaks is the subject of intensive investigation. Recent research in yeast and mammalian cells shows that ... -
Dna sequence polymorphisms in a panel of eight candidate bovine imprinted genes and their association with performance traits in irish holstein-friesian cattle
(Springer Nature, 2010-01-01)Background: Studies in mice and humans have shown that imprinted genes, whereby expression from one of the two parentally inherited alleles is attenuated or completely silenced, have a major effect on mammalian growth, ... -
Dna sequence polymorphisms within the bovine guanine nucleotide-binding protein gs subunit alpha (gsα)-encoding (gnas) genomic imprinting domain are associated with performance traits
(Springer Nature, 2011-01-01)Background: Genes which are epigenetically regulated via genomic imprinting can be potential targets for artificial selection during animal breeding. Indeed, imprinted loci have been shown to underlie some important ... -
Dna tests in prolific sheep from eight countries provide new evidence on origin of the booroola (fecb) mutation1
(Oxford University Press (OUP), 2002-06-01)Recent discoveries that high prolificacy in sheep carrying the Booroola gene (FecB) is the result of a mutation in the BMPIB receptor and high prolificacy in Inverdale sheep (FecX(1)) is the result of a mutation in the ... -
Dna-pk activity is associated with caspase-dependent myogenic differentiation
(Wiley-Blackwell, 2016-10-01)Differentiation of myoblasts into myotubes is essential for skeletal muscle development and regeneration. Caspase-3 and caspase-9 are required for efficient myoblast differentiation. The caspase-activated endonuclease ... -
Do anthropogenic, continental or coastal aerosol sources impact on a marine aerosol signature at mace head?
(Copernicus GmbH, 2014-10-10)Atmospheric aerosols have been sampled and characterised at the Mace Head north-east (NE) Atlantic atmospheric research station since 1958, with many interesting phenomena being discovered. However, with the range of new ... -
Do as I tweet, not as I do: comparing physical activity data between fitness tweets and Healthy People 2020
(JMIR Publications, 2015-11-30)Background: The goal of this research was to compare the self-reported estimates of daily physical-activity data provided to the Healthy People 2020 research team via a telephone survey to the mobile fitness app real-time ... -
Do big boats tow big nets?
(Oxford University Press (OUP), 2011-08-18)Fishing vessel capacity for trawlers is generally expressed in terms of length, tonnage, and engine power, assuming that a larger vessel has a greater fishing power. Management uses effort-control measures such as kW-day ... -
Do changes in current flow as a result of arrays of tidal turbines have an effect on benthic communities?
(Public Library of Science (PLoS), 2016-08-25)Arrays of tidal energy converters have the potential to provide clean renewable energy for future generations. Benthic communities may, however, be affected by changes in current speeds resulting from arrays of tidal ... -
Do city dashboards make sense? Conceptualising user experiences and challenges in using city dashboards. A case study
(Association for Computing Machinery (ACM), 2021-06-09)City dashboards present information about a city to a broad audience with some thought given as to how some of these audiences might understand the information. However, little research has looked at how ’citizens’ make ... -
Do farmers in Agri-Environmental schemes make appropriate ecological choices for the habitats on their farms? Modelling the biodiversity undertakings chosen within the Irish Rural Environment Protection Scheme
(National University of Ireland, Galway, 2011-07)Farmers participating in agri-environmental schemes (AESs) that are aimed at protecting biodiversity should ideally make decisions relating to the ecological management of their farms based on the habitat types found on ...