Dna repair: the importance of phosphorylating histone h2ax
Lowndes, Noel F.
Toh, Geraldine W.-L.
MetadataShow full item record
This item's downloads: 0 (view details)
Cited 133 times in Scopus (view citations)
Lowndes, Noel F. Toh, Geraldine W.-L. (2005). Dna repair: the importance of phosphorylating histone h2ax. Current Biology 15 (3), R99-R102
How phosphorylated histone H2AX, known as gamma-H2AX, functions in the cellular response to DNA double-strand breaks is the subject of intensive investigation. Recent research in yeast and mammalian cells shows that gamma-H2AX facilitates post-replicational DNA repair by recruiting cohesin, a protein complex that holds sister chromatids together.