Browsing by Author "Smith, Terry"
Now showing items 21-35 of 35
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Global gene expression analysis of the effects of Vinblastine on endothelial cells, when eluted from a thermo-responsive polymer
McLucas, Emily; Rochev, Yury; Carroll, W. M.; Smith, Terry (Wiley Online Library, 2006-06-30)In-stent restenosis remains a significant problem associated with bare metal stents. This drawback has prompted research into improving stent design and the development of novel coatings, including drug-eluting stents. A ... -
Improved method for direct pcr amplification from whole blood
McCusker, Jonathan; Dawson, Michael T.; Noone, David; Gannon, Frank; Smith, Terry (Oxford University Press (OUP), 1992-01-01) -
In-vitro cellular interaction of quantum dots and silicone surfaces
Bodi, Babu Rajendra Prasad (2011-09-30)The main hypothesis on which this study has been based is that the surface modification of nano-particles of different size (Quantum Dots) and varying nano-surfaces roughness (Silicones of nanosurface roughness) can make ... -
Long-term exposure of CdTe quantum dots on PC12 cellular activity and the determination of optimum non-toxic concentrations for biological use
Prasad, Babu R.; Nikolskaya, Natalia; Connolly, David; Smith, Terry; Rochev, Yury (2010)Background: The unique and tuneable photonic properties of Quantum Dots (QDs) have made them potentially useful tools for imaging biological entities. However, QDs though attractive diagnostic and therapeutic tools, have ... -
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
Morrison, John J.; Smith, Terry; O'Brien, Margaret; Fitzgibbon, Joan (Springer, 2009-01-08)Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are ... -
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
Fitzgibbon, Joan; Morrison, John J.; Smith, Terry; O'Brien, Margaret (BioMed Central, 2009-01-08)Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are not ... -
Novel multiplex isothermal nucleic acid amplification technologies for the detection of bacterial meningitis associated pathogens
Higgins, Owen (NUI Galway, 2019-02-28)Infectious diseases, caused by pathogenic microorganisms such as bacteria, fungi or viruses, are a leading cause of significant global morbidity and mortality, with over 10 million associated deaths reported each year. ... -
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design
O'Brien, Margaret; Smith, Terry (National Academy Of Sciences Of The United States Of America, 2013-10-23)Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were originally discovered in Oldenlandia affinis based on their use in ... -
Rapid real-time pcr detection of listeria monocytogenes in enriched food samples based on the ssra gene, a novel diagnostic target
O’ Grady, Justin; Sedano-Balbás, Sara; Maher, Majella; Smith, Terry; Barry, Thomas (Elsevier BV, 2008-02-01) -
Regulation Of Myometrial Gene Expression By Oestrogen And Progesterone: The Use Of A Cell Culture Model To Mimic The In Vivo Conditions Of Pregnant Human Uterus
Chandran, Sreenath (2012-12-31)Pregnancy and labour are physiological events controlled by a complex interplay between maternal and foetal factors. These processes are diverse and specific to each species, hence simple extrapolation from model organisms ... -
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction
Friel, Anne M,; Sexton, Donal J.; O'Reilly, Michael W.; Smith, Terry; Morrison, John J. (Society for Reproduction and Fertility, 2006-07-01)Pre eclampsia represents a state of increased or prolonged vasoconstriction, partially linked to the potent vasocontractile effect of isoprostanes. The process of Rho A-mediated calcium sensitisation is inherent to a state ... -
Solvent-selective routing for centrifugally automated solid-phase purification of RNA.
Clancy, Eoin; Coughlan, Helena; Helena, Thomas; Smith, Terry; Dwyer, Róisín M. (Springer, 2014-09-12)We present a disc-based module for rotationally controlled solid-phase purification of RNA from cell lysate. To this end, multi-stage routing of a sequence of aqueous and organic liquids into designated waste and elution ... -
Testes and brain gene expression in precocious male and adult maturing Atlantic salmon (Salmo salar)
Guiry, Aoife; Flynn, Denis; Hubert, Sophie; O'Keeffe, Allan M; LeProvost, Olivier; White, Samantha L; Forde, Patrick F; Davoren, Pamela; Houeix, Benoit; Smith, Terry; Wilkins, Noel P.; Cairns, Michael T. (BioMed Central, 2010)Background: The male Atlantic salmon generally matures in fresh water upon returning after one or several years at sea. Some fast-growing male parr develop an alternative life strategy where they sexually mature before ... -
Transcription factor binding site identification using the Self-Organizing Map
Mahony, Shaun; Hendrix, David; Golden, Aaron; Smith, Terry (Oxford Open Journals, 2005-05-01)Motivation: The automatic identification of over-represented motifs present in a collection of sequences continues to be a challenging problem in computational biology. In this paper, we propose a self-organizing map of ... -
Upregulation of PSCDBP, TLR2, TWIST1, FLJ35382, EDNRB, and RGS12 gene expression in human myometrium at labor.
O'Brien, Margaret; Morrison, John J.; Smith, Terry (Sage, 2008)The regulatory mechanisms underlying myometrial smooth muscle contractility during labor are poorly understood. The authors therefore investigated the transcriptional profile of the changes that occur in the human myometrium ...