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Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains
(Cambridge University Press (CUP), 2017-11-02)
Background. A range of endophenotypes characterise psychosis, however there has been limited work understanding if and how they are inter-related.
Methods. This multi-centre study includes 8754 participants: 2212 people ...
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the enigma schizophrenia consortium
(Wiley-Blackwell, 2017-03-29)
ObjectiveBased on the role of the superior temporal gyrus (STG) in auditory processing, language comprehension and self-monitoring, this study aimed to investigate the relationship between STG cortical thickness and positive ...
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the enigma consortium
(Cambridge University Press (CUP), 2017-05-26)
Background. Our understanding of the complex relationship between schizophrenia symptomatology and etiological factors can be improved by studying brain-based correlates of schizophrenia. Research showed that impairments ...
A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains
(Wiley-Blackwell, 2017-08-29)
This large multi-center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi-modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ...