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Loss of sigb in listeria monocytogenes strains egd-e and 10403s confers hyperresistance to hydrogen peroxide in stationary phase under aerobic conditions
(American Society for Microbiology, 2016-05-20)
SigB is the main stress gene regulator in Listeria monocytogenes affecting the expression of more than 150 genes and thus contributing to multiple-stress resistance. Despite its clear role in most stresses, its role in ...
Migrastatin analogues inhibit canine mammary cancer cell migration and invasion
(Public Library of Science (PLoS), 2013-10-08)
Background: Cancer spread to other organs is the main cause of death of oncological patients. Migration of cancer cells from a primary tumour is the crucial step in the complex process of metastasis, therefore blocking ...
The major autolysin is redundant forstaphylococcus aureususa300 lac je2 virulence in a murine device-related infection model
(Oxford University Press (OUP), 2016-04-03)
The major Staphylococcus aureus autolysin, Atl, has been implicated in attachment to surfaces and release of extracellular DNA during biofilm formation under laboratory conditions. Consistent with this, polyclonal antibodies ...
Exploring circulating micro-rna in the neoadjuvant treatment of breast cancer
(Wiley-Blackwell, 2016-01-30)
Breast cancer is the most frequently diagnosed malignancy amongst females worldwide. In recent years the management of this disease has transformed considerably, including the administration of chemotherapy in the neoadjuvant ...
Differential impact of hormone receptor status on survival and recurrence for her2 receptor-positive breast cancers treated with trastuzumab
(Springer Nature, 2017-04-04)
Introduction Hormone receptor status has major implications for treatment and survival of breast cancer. Yet the impact of hormone receptor status on outcome after Trastuzumab has received little attention. The objective ...
Fibronectin-binding proteins are required for biofilm formation by community-associated methicillin-resistantstaphylococcus aureusstrain lac
(Oxford University Press (OUP), 2014-04-01)
Community-associated methicillin-resistant Staphylococcus aureus of the USA300 lineage is emerging as an important cause of medical device-related infection. However, few factors required for biofilm accumulation by USA300 ...
Mesenchymal stem cell effects on t-cell effector pathways
(Springer Nature, 2011-01-01)
Mesenchymal stem (stromal) cells (MSCs) are rare, multipotent progenitor cells that can be isolated and expanded from bone marrow and other tissues. Strikingly, MSCs modulate the functions of immune cells, including T ...
Characterization of self-adjoint ordinary differential operators
(Elsevier BV, 2011-07-01)
The degradation of work and the end of the skilled emotion worker at aer lingus: is it all trolley dollies now?
(SAGE Publications, 2013-02-01)
The article focuses on emotional labour and self-identity at the Irish-owned Aer Lingus airline from 1998 to 2008. It has been suggested that emotional labour is likely to be an increasingly important feature of frontline ...
Macromolecular crowding meets oxygen tension in human mesenchymal stem cell culture - a step closer to physiologically relevant in vitro organogenesis
(Springer Nature, 2016-08-01)
Modular tissue engineering is based on the cells' innate ability to create bottom-up supramolecular assemblies with efficiency and efficacy still unmatched by man-made devices. Although the regenerative potential of such ...