Show simple item record

dc.contributor.authorAntoniades, Athos
dc.contributor.authorAristodimou, Aristos
dc.contributor.authorGeorgousopoulo, Christos
dc.contributor.authorForgó, Nikolaus
dc.contributor.authorGledson, Ann
dc.contributor.authorHasapis, Panagiotis
dc.contributor.authorVandeleur, Caroline
dc.contributor.authorPerakis, Konstantinos
dc.contributor.authorSahay, Ratnesh
dc.contributor.authorMehdi, Muntazir
dc.contributor.authorDemetriou, Christiana A.
dc.contributor.authorStrippoli, Marie-Pierre F.
dc.contributor.authorGiotaki, Vasiliki
dc.contributor.authorIoannidi, Myrto
dc.contributor.authorTian, David
dc.contributor.authorTozzi, Federica
dc.contributor.authorKeane, John
dc.contributor.authorPattichis, Constantinos
dc.date.accessioned2018-07-31T12:04:49Z
dc.date.available2018-07-31T12:04:49Z
dc.date.issued2017-03-22
dc.identifier.citationAntoniades, Athos,Aristodimou, Aristos,Georgousopoulos, Christos, Forgó, Nikolaus,Gledson, Ann,Hasapis, Panagiotis,Vandeleur, Caroline,Perakis, Konstantinos,Sahay, Ratnesh,Mehdi, Muntazir,Demetriou, Christiana A.,Strippoli, Marie-Pierre F.,Giotaki, Vasiliki,Ioannidi, Myrto,Tian, David,Tozzi, Federica,Keane, John,Pattichis, Constantinos. (2017). Advancing clinical research by semantically interconnecting aggregated medical data information in a secure context. Health and Technology, 7(2), 223-240. doi: 10.1007/s12553-017-0188-0en_IE
dc.identifier.issn2190-7196
dc.identifier.issn2190-7188
dc.identifier.urihttp://hdl.handle.net/10379/7446
dc.description.abstractElectronic Health Records (EHRs) contain an increasing wealth of medical information. When combined with molecular level data, they enhance the understanding of the underlying biological mechanisms of diseases, enabling the identification of key prognostic biomarkers to disease and treatment outcomes. However, the European healthcare information space is fragmented due to the lack of legal and technical standards, cost effective platforms, and sustainable business models. There is a clear need for a framework facilitating the efficient and homogenized access to anonymized distributed EHRs, merged from multiple data sources into a single data analysis space. In this paper we present the outcomes of Linked2Safety, a project that proposes a solution to these problems by providing a semantically interconnected approach to sharing aggregate data in the form of data cubes. This approach eliminates the risks associated with sharing pseudoanonymized (and therefore still personal) data while enabling the multi-source, multi-type analysis of health data through a single web based secure access platform. The Linked2Safety system is evaluated by external to the project Medical science analysts, Analytic methodology engineers and Data providers with respect to five specific dimensions of the system (analysis space, linked data space, usability of the system, legal and ethical issues, and value of the system) in this paper. For all five dimensions that were examined, the participantsâ perceptions were overwhelmingly positive.en_IE
dc.description.sponsorshipThe research leading to these results was conducted as part of the project A next-generation secure linked data medical information space for semantically-interconnecting electronic health records and clinical trials systems advancing patients safety in clinical research (Linked2Safety) that received funding from the European Union’s Seventh Framework Programme (FP7/2007–2013) under Grant Agreement No 288328.en_IE
dc.formatapplication/pdfen_IE
dc.language.isoenen_IE
dc.publisherSpringer Verlagen_IE
dc.relation.ispartofHealth and Technologyen
dc.subjectSemantic interoperabilityen_IE
dc.subjectLinked2Safetyen_IE
dc.subjectElectronic health recordsen_IE
dc.subjectPersonal data protectionen_IE
dc.subjectAnonymityen_IE
dc.subjectAdverse event predictionen_IE
dc.subjectGenetic analysisen_IE
dc.titleAdvancing clinical research by semantically interconnecting aggregated medical data information in a secure contexten_IE
dc.typeArticleen_IE
dc.date.updated2018-07-06T16:27:59Z
dc.identifier.doi10.1007/s12553-017-0188-0
dc.local.publishedsourcehttps:/dx.doi.org/10.1007/s12553-017-0188-0en_IE
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funderFP7 Information and Communication Technologiesen_IE
dc.internal.rssid14544081
dc.local.contactRatnesh Nandan Sahay, Deri, Dangan Business Park, Nui Galway. 5253 Email: ratnesh.sahay@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionACCEPTED
dcterms.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::ICT/288328/EU/A NEXT-GENERATION, SECURE LINKED DATA MEDICAL INFORMATION SPACE FOR SEMANTICALLY-INTERCONNECTING ELECTRONIC HEALTH RECORDS AND CLINICAL TRIALS SYSTEMS ADVANCING PATIENTS SAFETY IN CLINICAL RESEARCH/LINKED2SAFETYen_IE
nui.item.downloads61


Files in this item

Attribution-NonCommercial-NoDerivs 3.0 Ireland
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. Please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.

The following license files are associated with this item:

Thumbnail

This item appears in the following Collection(s)

Show simple item record