Now showing items 1-10 of 122
Anti-donor immune responses elicited by allogeneic mesenchymal stem cells and their extracellular vesicles: Are we still learning?
(Frontiers Media, 2017-11-24)
Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppr ...
Minimum information about T Regulatory Cells: A step toward reproducibility and standardization
(Frontiers Media, 2018-01-15)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing ...
Anandamide modulation of endotoxin-induced inflammation
(OMICS International, 2013-12-20)
The endocannabinoid system is comprised of the CB1 and CB2 receptors, the naturally occurring endogenous ligands, anandamide (AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes involved in their synthesis and ...
A comparison of the teamwork attitudes and knowledge of Irish surgeons and U.S Naval aviators.
Poor teamwork skills are contributors to poor performance and mishaps in high risk work settings, including the operating theatre. A questionnaire was used to assess the attitudes towards, and knowledge of, Irish surgeons ...
The effect of pain on cognitive function: a review of clinical and preclinical research.
Cognitive impairment is commonly associated with the pain experience. This impairment represents a major obstacle to daily activities and rehabilitation, especially in the chronic pain population. Here we review clinical ...
Identifying and addressing the limitations of safety climate surveys.
This paper reports the descriptive analysis of a large sample of safety climate survey data (n = 110,014) collected over 10 years from U.S. Naval aircrew using the Command Safety Assessment Survey (CSAS).
vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis
Recent efforts in osteoarthritis (OA) research have highlighted synovial inflammation and involvement of immune cells in disease onset and progression. We sought to establish the in-vivo immune response in collagenase-induced ...
Out-of-hospital cardiac arrest attended by ambulance services in Ireland: first 2 years' results from a nationwide registry
(BMJ Publishing Group, 2016-10-20)
Background National data collection provides information on out-of-hospital cardiac arrest (OHCA) incidence, management and outcomes that may not be generalisable from smaller studies. This retrospective cohort study ...
Design of a smartphone application with integrated Functional Electrical Stimulation (FES) treatment randomization and On-The-Fly Stimulus Parameter Adjustment for streamlining the clinical evaluation of FES protocols
(OMICS International, 2016-03-14)
The clinical application of Functional Electrical Stimulation (FES) has evolved over the last five decades. However, the use of the Randomized Control Trial (RCT) methodology in evaluating the clinical effectiveness of new ...
These shoes are made for walking: sensitivity performance evaluation of commercial activity monitors under the expected conditions and circumstances required to achieve the international daily step goal of 10,000 steps
(Public Library of Science, 2016-05-11)
IntroductionPhysical activity is a vitally important part of a healthy lifestyle, and is of major benefit to both physical and mental health. A daily step count of 10,000 steps is recommended globally to achieve an appropriate ...