Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia

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Date
2017-06-11Author
Colgan, Niall
O'Reilly, David
Holleran, Laurena
Ahmed, Mohamed
McDonald, Colm
Cannon, Dara M.
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Colgan, Niall, O'Reilly, David, Holleran, Laurena, Ahmed, Mohamed , McDonald, Colm, & Cannon, Dara M. (2017). Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia. Paper presented at the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), Tampere, Finland.
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Abstract
Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the as-sumption of a Gaussian distribution of diffusion in neu-ral architecture. Free water modelling aims to address this issue, and we present the second application of FA of tissue and free water mapping.