Browsing School of Medicine by Title
Now showing items 1-20 of 336
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The 100 most cited articles on healthcare simulation: a bibliometric review
(Lippincott, Williams & Wilkins, 2018-06)This article provides an overview and synthesis of the 100 most cited healthcare simulation publications to provide insight into the articles that have shaped current knowledge and practice. Searches of the Scopus and Web ... -
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
(Wiley, 2012-07)A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these ... -
The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy
(2013)Objective: To study 5-HT transport and 5-HT1A receptors in temporal lobe epilepsy (TLE) and depression.Methods: Thirteen patients had PET with [C-11]DASB for 5-HTT and [F-18]FCWAY for 5-HT1A receptor binding, MRI, and ... -
6-iodonordihydrocapsaicin
(2009)6-Iodonordihydrocapsaicin was first synthesized by Giovanni Appendino at the Department of Chemical, Food, Pharmaceutical and Pharmacological Sciences (DiSCAFF), Novara, Italy, while developing a series of halogenated ... -
Acute ischemic stroke secondary to cardiac embolus of a ‘foreign body’ material after a redo sternotomy for mitral valve replacement: A case report
(SAGE Publications, 2018-11-14)Cardiac surgery has been shown to be associated with increased risk of acute ischemic stroke. This report presents a case of a successful mechanical embolectomy procedure to treat a patient for an acute ischemic stroke, ... -
Adenovirus-mediated and targeted expression of the sodium-iodide symporter permits in vivo radioiodide imaging and therapy of pancreatic tumors
(Mary Ann Liebert, 2006-06-15)Pancreatic cancer is the fourth leading cause of cancer death in the United States. It is highly aggressive with no uniformly effective chemotherapy available for metastatic disease. The sodium–iodide symporter (NIS) is a ... -
Adjustment disorder and suicidal behaviours presenting in the general medical setting: A systematic review
(MDPI, 2019-08-18)Background: Adjustment disorder (AD) is a condition commonly encountered by clinicians in emergency departments and liaison psychiatry settings and has been frequently reported among patients presenting with suicidal ... -
The administration of rtPA before mechanical thrombectomy in acute ischemic stroke patients is associated with a significant reduction of the retrieved clot area but it does not influence revascularization outcome
(Springer, 2020-09-16)Both intravenous thrombolysis (IVT) and mechanical thrombectomy (MT) are evidence-based treatments for acute ischemic stroke (AIS) in selected cases. Recanalization may occur following IVT without the necessity of further ... -
Adverse early life experiences are associated with changes in pressure and cold pain sensitivity in young adults
(AME Publishing, 2020-07)[No abstract available] -
Adverse effects of amoxicillin for acute lower respiratory tract infection in primary care: Secondary and subgroup analysis of a randomised clinical trial
(MDPI, 2017-12-13)A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, and found ... -
Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials
(Elsevier, 2018-04-25)Background Fluoroquinolones (FQs) are second line antimicrobial agents. Once the decision to prescribe an antimicrobial is made, its choice should be based on both the benefits and harms. This systematic review quantifies ... -
Alterations in the central opioid system following acute swim stress and olfactory bulbectomy in the rat
(Elsevier, 2019-12-13)Introduction: Stress is a major component of many animal models of depression, induced acutely as in the forced swim test, or more long-term in the olfactory bulbectomy (OB) and chronic mild stress models [1]. The central ... -
Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala
(Wiley, 2013-08-29)The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ... -
Am I being watched? The role of researcher presence on toddlers’ behaviour during ‘everyday’ pain experiences: a pilot study
(Taylor & Francis, 2019-12-31)Objective: Paediatric research on 'everyday' pain experiences is sparse, stemming from a lack of appropriate methodologies. We explored the feasibility of two methodologies for conducting naturalistic observations of ... -
Analysing complaints about primary care with the healthcare complaints analysis tool (General Practice): A user’s guide
(National University of Ireland Galway, 2022-01)General practice is a vital aspect of the health service, with large numbers of patient contacts every year1. While general practice is often seen as inherently less risky than secondary care2, errors have been found to ... -
An analysis of general practitioners’ perspectives on patient safety incidents using critical incident technique interviews
(Oxford University Press (OUP), 2019-03-30)Background General practitioners report difficulty in knowing how to improve patient safety. Objectives To analyse general practitioners’ perspectives of contributing factors to patient safety incidents by collecting ... -
Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury
(Elsevier, 2018-09-26)Background: The use of animals to model spinal cord injury (SCI) requires extensive post-operative care and can be expensive, which makes an altemative model extremely attractive. The use ofex vivo slice cultures is an ... -
Analysis of thermal effects from pulsed field ablation
(Oxford University Press, 2023-11-09)Background Pulsed field ablation (PFA) has been described as non-thermal, but abundant data exist in oncology applications [1-3], and growing data are emerging in cardiology [4], highlighting that thermal effects are in ... -
Anandamide modulation of endotoxin-induced inflammation
(OMICS International, 2013-12-20)The endocannabinoid system is comprised of the CB1 and CB2 receptors, the naturally occurring endogenous ligands, anandamide (AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes involved in their synthesis and ... -
Animal models of focal cerebral ischaemia and haemorrhage transformation: considerations in experimental stroke study design
(Bentham Science Publishers, 2017)Background: Ischaemic stroke is often complicated with haemorrhage within the infarct zone or in a remote location especially when treated with intravenous thrombolysis and/or thrombectomy. While these early recanalisation ...