Show simple item record

dc.contributor.authorLohfeld, Stefan
dc.contributor.authorTyndyk, M.A.
dc.contributor.authorCahill, S.
dc.contributor.authorFlaherty, N.
dc.contributor.authorBarron, Valerie
dc.contributor.authorMcHugh, Peter
dc.date.accessioned2013-09-24T14:11:15Z
dc.date.available2013-09-24T14:11:15Z
dc.date.issued2010
dc.identifier.citationLohfeld, S; Tyndyk, MA; Cahill, S; Flaherty, N; Barron, V; McHugh, PE (2010) 'A method to fabricate small features on scaffolds for tissue engineering via selective laser sintering'. Journal of Biomedical Science and Engineering, .en_US
dc.identifier.urihttp://hdl.handle.net/10379/3664
dc.description.abstractPurpose:Selective laser sintering (SLS) is a rapid prototyping technique applied to produce tissue-engineering scaffolds from powder materials. The standard scanning technique, however, often produces struts of extensive thickness, which means fabrication of highly porous scaffolds with small overall dimensions is quite difficult. Nevertheless, this study aims to overcome this shortfall. Design/methodology/approach:To this end, three scanning methods were evaluated in terms of minimum feature size and freedom of design, using a test polyamide (PA) material. Polycaprolactone (PCL) was then employed to create highly porous 3D scaffolds using the preferred scanning method to produce thin struts.Findings:While in normal scanning mode some features were well above the laser spot diameter, strut thicknesses below the laser spot diameter were achieved when using the outline scan function for PA material. Those achieved for PCL were slightly higher and in the 500-800 µm range, with an average pore size of 400 μm. Investigations on the properties of the scaffolds revealed an effective compression modulus of the PCL scaffold of 6.5 MPa. Furthermore, there was no change in physical or chemical properties when the scaffolds were stored in a physiological environment for 7 weeks. Originality/ value: Though SLS is considered as a fabrication technique for tissue engineering scaffolds, actually produced scaffolds did not comply with porosity requirements and limitations of the SLS process in producing features at the size of the laser beam spot have not been discussed. The present paper shows the capabilities of the SLS process based on two materials and presents a method to minimize feature size in scaffolds.en_US
dc.formatapplication/pdfen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Biomedical Science and Engineeringen
dc.subjectSelective Laser Sinteringen_US
dc.subjectRapid Prototypingen_US
dc.subjectScaffoldsen_US
dc.subjectPolycaprolactoneen_US
dc.subjectTissue Engineeringen_US
dc.titleA method to fabricate small features on scaffolds for tissue engineering via selective laser sinteringen_US
dc.typeArticleen_US
dc.date.updated2013-09-13T15:48:14Z
dc.identifier.doidoi:10.4236/jbise.2010.32019
dc.local.publishedsourcehttp://dx.doi.org/10.4236/jbise.2010.32019en_US
dc.description.peer-reviewedpeer-reviewed
dc.contributor.funder|~|EU|~|IRCSET|~|PRTLI|~|
dc.internal.rssid1328866
dc.local.contactStefan Lohfeld, Mechanical & Biomedical Eng, Engineering Building Eng-1042, Nui Galway. 2963 Email: stefan.lohfeld@nuigalway.ie
dc.local.copyrightcheckedYes
dc.local.versionACCEPTED
nui.item.downloads459


Files in this item

Attribution-NonCommercial-NoDerivs 3.0 Ireland
This item is available under the Attribution-NonCommercial-NoDerivs 3.0 Ireland. No item may be reproduced for commercial purposes. Please refer to the publisher's URL where this is made available, or to notes contained in the item itself. Other terms may apply.

The following license files are associated with this item:

Thumbnail

This item appears in the following Collection(s)

Show simple item record