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TGF-ß1-Licensed Murine MSCs show superior therapeutic efficacy in modulating corneal allograft immune rejection In Vivo
(Elsevier, 2020-05-29)
Mesenchymal stromal cells (MSCs) are a promising therapeutic option for multiple immune diseases/disorders; however, efficacy of MSC treatments can vary significantly. We present a novel licensing strategy to improve the ...
Human monocyte subset distinctions and function: Insights from gene expression analysis
(Frontiers Media, 2020-06-04)
Monocytes are a highly plastic innate immune cell population that displays significant heterogeneity within the circulation. Distinct patterns of surface marker expression have become accepted as a basis for distinguishing ...
Burden of chronic kidney disease and rapid decline in renal function among adults attending a hospital-based diabetes center in Northern Europe
(BMJ Publishing Group, 2021-06-14)
Introduction This study aimed to determine the prevalence of diabetic kidney disease (DKD) and rapid renal function decline and to identify indices associated with this decline among adults attending a diabetes center in ...
Editorial: Innovative biologics and drugs to target renal inflammation
(Frontiers Media, 2020-02-06)
[No abstract available]
Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade
(Elsevier, 2020-01-28)
A little over 10 years ago, the therapeutic potential of mesenchymal stromal cells (MSCs) for the treatment of acute kidney injury (AKI) was becoming widely recognized. Since then, there has been further intensive study ...
Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance
(AlphaMed Press and Wiley, 2020-01-29)
The immunomodulatory potential of mesenchymal stromal cells (MSCs) and regulatory T cells (T-reg) is well recognized by translational scientists in the field of regenerative medicine and cellular therapies. A wide range ...
Progress toward the clinical application of mesenchymal stromal cells and other disease-modulating regenerative therapies
(American Society of Nephrology, 2021-01-27)
Drawing from basic knowledge of stem cell biology, embryonic development, wound healing and aging, regenerative medicine seeks to develop therapeutic strategies that complement or replace conventional treatments by actively ...