Browsing Regenerative Medicine Institute (REMEDI) by Author "Sanz-Nogués, Clara"
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Current good manufacturing practice considerations for mesenchymal stromal cells as therapeutic agents
Sanz-Nogués, Clara; O'Brien, Timothy (Elsevier, 2021-05-05)Producing human mesenchymal stromal cells (MSCs) for clinical use requires adherence to current good manufacturing practice (cGMP) standards. This is necessary for ensuring standardization and reproducibility through the ... -
In vitro models for assessing therapeutic angiogenesis
Sanz-Nogués, Clara; O'Brien, Timothy (Elsevier, 2016-06-01)Arterial obstruction leading to ischemia causes a reduction of oxygen and nutrient supply to distal tissues. The physiological response to tissue ischemia triggers a cascade of events that results in the development of ... -
Inefficiency in macromolecular transport of SCS‐based microcapsules affects viability of primary human mesenchymal stem cells but not of immortalized cells
Sanz-Nogués, Clara; Horan, Jason; Thompson, Kerry; Howard, Linda; Ryan, Gerard; Kassem, Moustapha; O'Brien, Timothy (Wiley, 2015-05-01)Microcapsules made of sodium cellulose sulphate (SCS) and poly-diallyl-dimethyl-ammonium chloride (pDADMAC) have been employed to encapsulate a wide range of established cell lines for several applications. However, little ...