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The influence of collagen isolation, cross-linking and sterilisation on macrophage response
(2018-03-07)
Collagen-based devices are frequently associated with foreign body response. Although several pre- (e.g. species, state of animal, tissue, isolation protocol) and post- (e.g. cross-linking, scaffold architecture, sterilisation) ...
The role of matrix properties and extrinsic loading in osteoblast-osteocyte differentiation in tissue engineered scaffolds
(2018-02-05)
Bone tissue engineering is a promising field with the potential to generate tissue substitutes, by taking advantage of mesenchymal stem cells ability to grow and produce tissue substitutes under specific physical conditions. ...
Towards inherently adaptive first person shooter agents using reinforcement learning
(2015-09-30)
Reinforcement learning (RL) is a paradigm which involves an agent interacting with an environment. The agent carries out actions in the environment and receives positive reinforcement for actions that are deemed “good” and ...
Development of efficient data assimilation methods for solute transport problems
(NUI Galway, 2018-09-18)
The solution of marine contaminant transport problems is a significant research topic in civil engineering. Typically, the problem is represented as a partial differential equation described by the non-stationary, ...
Contributions to deep learning methodologies
(NUI Galway, 2018-10-26)
In recent years the Deep Neural Networks (DNN) has been using widely in a big range of
machine learning and data-mining purposes. This pattern recognition approach can handle
highly nonlinear problems.
In this work, ...
Calibrated whole building energy simulation: An evidence-based methodology
(2011-01)
Climate change, driven by global energy consumption, is one of the major challenges to humanity today. The buildings sector consumes a significant portion of global energy resources and much of this is due to inefficient ...
Nature Inspired Computational Optimisation Methods for System Dynamics
(2012-06-10)
This thesis aims to provide the state of the art "nature-inspired computing" (NIC) approaches and investigate their applications in system dynamics (SD) models. Specifically, we will focus on particle swarm optimisation ...
Microbial Lipid production from potato processing waste water and simultaneous nutrient removal using oleaginous fungi
(2012-10-09)
Microbial lipids can be used as a feedstock for biodiesel production, and use of biowastes as the substrate for microbial lipid production can reduce its production cost. The aims of this research include: (i) isolation ...
A Probabilistic Framework Based on Mathematical Models with Application to Medical Data Streams
(2012-08-01)
This thesis presents a new probability-based framework which exploits existing domain knowledge in the form of mathematical models and uses real-time data streams to individualise model parameters.
We apply this new ...
Ultrawideband Radar for the Early Detection of Cancer Within the Heterogeneous Breast
(2012-01-18)
Ultrawideband (UWB) microwave imaging is an emerging breast screening modality
based on the electromagnetic reflections generated by the dielectric contrast between
soft tissue types within the breast at microwave ...