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The kinesin KIF18B interacts with 53BP1 and is required for efficient double strand break repair
(2015-11-19)
Genetic changes can lead to detrimental genomic instability, mutagenesis, oncogenesis and premature aging. The DNA damage response (DDR) is responsible for safeguarding the genome from such harmful alterations.
53BP1 ...
Habitats plants and invertebrates as tools for rapid identification of high nature value farmland
(2015-02-13)
The EU, in recognition that low intensity farming plays an important role in conserving biodiversity, is committed to identifying and protecting High Nature Value (HNV) farming. Most methods used to date to delineate areas ...
Infilling wetlands with construction and demolition (C&D) waste: Influence on land use, plant/dipteran communities and metal contamination
(2015-01-28)
Construction and demolition (C&D) waste, comprised of sand, stone, concrete, bitumen and other wastes from building sites, is one of the largest fractions of waste produced internationally. It frequently ends up being used ...
Hydrolysis, methanogenesis and bioprocess performance during low-temperature anaerobic digestion of dilute wastewater
(2015-04-28)
Anaerobic digestion (AD) technologies represent sustainable and appropriate systems for the treatment of organic wastewaters. Lettinga et al (1987) stated, "A satisfactory application to raw domestic sewage would represent ...
Identification of novel drug combinations for haematological malignancies
(2015-01-29)
TNF-related apoptosis ligand (TRAIL) is a tumour selective cytokine with potential anti-cancer activity which is currently in clinical trials. Haematological malignancies along with several other cancers have showed varied ...
Ctrl-atl-delete: Re-thinking the mechanisms of biofilm formation by staphylococci
(2015-04-07)
Biofilm formation by staphylococci on implanted medical devices represents a major virulence mechanism and a serious threat to hospital patients. Staphylococcus aureus strains including, methicillin-resistant S. aureus ...
Exploring synthetic strategies towards novel magnetic materials - a structural, magnetic and spectroscopic study
(2015-09-03)
This thesis reports the exploration of various synthetic strategies towards the synthesis of novel magnetic materials, which were studied both structurally and spectroscopically. An outline of results chapters is given ...