The genes encoding the transcription factor Six1, and its co-factor Eya1 together mark the embryonic territory - the pan-placodal ectoderm (PPE) - that gives rise to most cranial sense organs in vertebrates. Mutation of ...

A range of different genetic processes can facilitate species-specific adaptations. These include orphan genes and genes subject to genomic imprinting. All organisms are known to contain unique genes that have no recognizable ...

Hydractinia is a colony forming marine invertebrate and a member of the phylum Cnidaria. Members of this genus have been models for developmental biologists for over a century and feature many characters of evolutionary ...

Components of the centrosome have been reported to have a role in the DNA Damage Response (DDR) pathway. Cep164, a protein localised to the distal appendages of centrioles, is theorised to play a part in the DDR. As with ...

Campylobacter jejuni (C. jejuni) is a zoonotic pathogen of major public health importance and is the leading cause of gastroenteritis woldwide. Poultry is regarded as one of the most important reservoirs for Campylobacter ...

Sialic acids are a family of 9 carbon α-keto acid monosaccharides. Owing to their terminal position on glycans, sialic acids are involved in cell adhesion and recognition events, host pathogen interactions, immune regulation ...

Cell wall glycan-directed monoclonal antibodies (mAbs) are sensitive tools for the detection of wall components in vitro (glycome profiling) and in situ (immunolocalization). Although extensively applied to land plant and ...

The objectives of this thesis were to 1) explore the glycosylation of major bovine milk proteins, 2) investigate the effect of lactational stage on glycan structures and 3) examine how these documented changes may influence ...