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Estrogen withdrawal in osteocytes results in altered integrin function, primary cilium elongation, and increased pro-osteoclastogenic signalling
(NUI Galway, 2020-06-28)
Osteocytes are the main mechanosensitive cells within bone. They detect changes in the mechanical environment and transduce them into biochemical responses (RANKL, OPG, and sclerostin) that regulate bone remodelling by ...