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Dissecting the pan-placodal gene regulatory network reveals novel interactions driving sense organ development in vertebrates
(2016-02-17)
The genes encoding the transcription factor Six1, and its co-factor Eya1 together mark the embryonic territory - the pan-placodal ectoderm (PPE) - that gives rise to most cranial sense organs in vertebrates. Mutation of ...
Regulation of Six1 and Eya1 during the formation of the preplacodal ectoderm in xenopus - towards a gene regulatory network of the developing neural plate border
(2017-01-06)
Cranial placodes are ectodermal thickenings in vertebrate embryos that give rise to many
sense organs and ganglia. All placodes arise from a common precursor, the pre-placodal
ectoderm (PPE). The latter develops during ...