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The cannabinoid type-2 (CB2) receptor as a target for anti-inflammatory disease modification in Parkinson's disease
(2016-08-04)
Parkinson’s disease is a multifaceted neurodegenerative disorder with no curative treatment. A key aspect in the pathogenesis of Parkinson’s disease is inflammation, which is initially triggered by dying neurons and which ...
The potential of GDF5-functionalised collagen hydrogels to enhance dopaminergic cell replacement therapies for Parkinson's disease
(NUI Galway, 2020-03-05)
Parkinson’s disease is a progressive neurodegenerative disorder associated with the loss of dopaminergic neurons from the substantia nigra and striatum. Over time, the gold standard pharmacotherapy, L-dopa, loses its ...