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Investigating the mechanism of action and potential efficacy of Apolipoprotein E mimetics as therapeutic agents for the treatment of metastatic prostate cancer
(2017-10-04)
Prostate cancer is the most prevalent non cutaneous cancer diagnosed in Irish men and the third leading cause of death in males annually in Ireland. Therapeutic strategies currently consist of prostatectomy or radiation ...
Role of MicroRNAs and unfolded protein response in breast cancer
(2017-11-24)
Stressful conditions of the tumour microenvironment which overwhelm the folding capacity of the endoplasmic reticulum (EnR) activate an evolutionary conserved signalling pathway known as the unfolded protein response (UPR). ...