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Investigation of non-covalent interactions of metal complexes with DNA in cell-free systems
(Schweizerische Chemische Gesellschaft, 2017-03-01)
Non-covalent interactions of metallo compounds with DNA range from the simple, unspecific electrostatic binding of a positively charged metal complex to the sequence-selective recognition of DNA binding sites due to shape, ...
N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines
(Elsevier, 2018-12-04)
1,5-Dideoxy-1,5-imino-l-fucitol (1-deoxyfuconojirimycin, DFJ) is an iminosugar that inhibits fucosidases. Herein, N-alkyl DFJs have been synthesised and tested against the ¿-fucosidases of T. maritima (bacterial origin) ...
A Weibull-count approach for handling under- and overdispersed longitudinal/clustered data structures
(SAGE Publications, 2018-07-30)
A Weibull-model-based approach is examined to handle under- and overdispersed discrete data in a hierarchical framework. This methodology was first introduced by Nakagawa and Osaki (1975, IEEE Transactions on Reliability, ...
Initial stresses in elastic solids: Constitutive laws and acoustoelasticity
(2011)
On the basis of the nonlinear theory of elasticity, the general constitutive equation for an isotropic hyperelastic solid in the presence of initial stress is derived. This derivation involves invariants that couple the ...
Models for overdispersed data in entomology
(Springer, Cham, 2014-09-17)
Entomological data are often overdispersed, characterised by a larger variance than assumed by simple standard models. It is important to model overdispersion properly in order to avoid incorrect and misleading inferences. ...
Standard protocols for antimicrobial susceptibility testing of Vibrionaceae isolated from aquatic animals
(European Association of Fish Pathologists, 2018-07-18)
A review of the relevant literature has shown that it is safe to recommend that the antimicrobial
susceptibility of the species of the Vibrionaceae most commonly isolated from aquatic animals can
be established using ...
Portable X-ray fluorescence for the detection of POP-BFRs in waste plastics
(Elsevier, 2018-05-26)
The purpose of this study was to establish the efficacy of portable X-ray fluorescence (XRF) instrumentation as a screening tool for a variety of end of life plastics which may contain excess amounts of brominated flame ...
Investigating native state fluorescence emission of Immunoglobulin G using polarized Excitation Emission Matrix (pEEM) spectroscopy and PARAFAC
(Elsevier, 2018-12-20)
Intrinsic fluorescence spectroscopy (IFS) measurements for protein structural analysis can be enhanced by the use of anisotropy resolved multidimensional emission spectroscopy (ARMES). ARMES attempts to overcome the ...
Fluorescence analysis of thermoresponsive polymers
(Springer Verlag, 2015-12-18)
The use of microscale thin polymer films is widespread in biomedical science and engineering, with applications in areas such as tissue engineering, drug delivery, microfluidic devices, bio-adhesion mediators, and ...
Accurate anisotropy recovery from fluorophore mixtures using Multivariate Curve Resolution (MCR)
(Elsevier, 2017-11-22)
Anisotropy resolved multidimensional emission spectroscopy (ARMES) provides valuable insights into multi-fluorophore systems like proteins that have complex overlapping emission bands. The method combines multidimensional ...