Browsing College of Science by Author "El-Nahas, Ahmed"
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Oxidative stress induced by Pt(IV) pro-drugs based on the cisplatin scaffold and indole carboxylic acids in axial position
Tolan, Dina; Gandin, Valentina; Morrison, Liam; El-Nahas, Ahmed; Marzano, Cristina; Montagner, Diego; Erxleben, Andrea (Nature Publishing Group, 2016-06-11)The use of Pt(IV) complexes as pro-drugs that are activated by intracellular reduction is a widely investigated approach to overcome the limitations of Pt(II) anticancer agents. A series of ten mono- and bis-carboxylated ...