Browsing College of Science by Subject "SURFACE BINDING"

Now showing items 1-2 of 2

    • Influence of protein (human galectin-3) design on aspects of lectin activity 

      Caballero, Gabriel Garcia; Beckwith, Donella; Shilova, Nadezhda, V.; Gabba, Adele; Kutzner, Tanja J.; Ludwig, Anna-Kristin; Manning, Joachim C.; Kaltner, Herbert; Sinowatz, Fred; Cudic, Mare; Bovin, Nicolai, V.; Murphy, Paul V.; Gabius, Hans-Joachim (Springer, 2020-04-25)
      The concept of biomedical significance of the functional pairing between tissue lectins and their glycoconjugate counterreceptors has reached the mainstream of research on the flow of biological information. A major challenge ...

    • Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design 

      Roy, René; Cao, Yihong; Kaltner, Herbert; Kottari, Naresh; Shiao, Tze Chieh; Belkhadem, Karima; André, Sabine; Manning, Joachim C.; Murphy, Paul V.; Gabius, Hans-Joachim (Springer, 2016-06-24)
      A hallmark of endogenous lectins is their ability to select a few distinct glycoconjugates as counterreceptors for functional pairing from the natural abundance of cellular glycoproteins and glycolipids. As a consequence, ...